| pubmed-article:5721465 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:5721465 | lifeskim:mentions | umls-concept:C0036945 | lld:lifeskim |
| pubmed-article:5721465 | lifeskim:mentions | umls-concept:C0221908 | lld:lifeskim |
| pubmed-article:5721465 | lifeskim:mentions | umls-concept:C0021853 | lld:lifeskim |
| pubmed-article:5721465 | lifeskim:mentions | umls-concept:C0009368 | lld:lifeskim |
| pubmed-article:5721465 | lifeskim:mentions | umls-concept:C0026682 | lld:lifeskim |
| pubmed-article:5721465 | lifeskim:mentions | umls-concept:C0037025 | lld:lifeskim |
| pubmed-article:5721465 | lifeskim:mentions | umls-concept:C0220781 | lld:lifeskim |
| pubmed-article:5721465 | pubmed:issue | 1 | lld:pubmed |
| pubmed-article:5721465 | pubmed:dateCreated | 1969-6-19 | lld:pubmed |
| pubmed-article:5721465 | pubmed:abstractText | 1. Sheep colonic mucin contains three types of sialic acids, separable from the macrostructure by mild acidic hydrolysis. These are composed chiefly of N-acetyl-and N-glycollyl-neuraminic acid in ratios between 1:1.2 and 1:3.5 for different preparations of the mucin. The third sialic acid appears to be a diacetylated neuraminic acid. 2. A particle-free enzyme preparation, obtained from sheep colonic mucosa by gentle homogenization and high-speed centrifugation, catalyses a series of reactions involving N-acylamino sugars and leading to the formation of sialic acids in vitro: (i) phosphorylation by ATP of d-glucosamine, N-acetyl-and N-glycollyl-d-glucosamine; (ii) conversion of N-acetylglucosamine 6-phosphate into N-acetyl-d-glucosamine 1-phosphate; (iii) formation of sialic acids from phosphoenolpyruvate and N-acetyl- or N-glycollyl-d-glucosamine; (iv) formation of N-acetylneuraminic acid from uridine diphospho-N-acetylglucosamine or from N-acetylmannosamine; (v) incorporation of l-[U-(14)C]serine into the mucin by whole mucosal preparations. | lld:pubmed |
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| pubmed-article:5721465 | pubmed:language | eng | lld:pubmed |
| pubmed-article:5721465 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:5721465 | pubmed:citationSubset | IM | lld:pubmed |
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| pubmed-article:5721465 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:5721465 | pubmed:month | Jan | lld:pubmed |
| pubmed-article:5721465 | pubmed:issn | 0264-6021 | lld:pubmed |
| pubmed-article:5721465 | pubmed:author | pubmed-author:KentP WPW | lld:pubmed |
| pubmed-article:5721465 | pubmed:author | pubmed-author:DraperPP | lld:pubmed |
| pubmed-article:5721465 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:5721465 | pubmed:volume | 106 | lld:pubmed |
| pubmed-article:5721465 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:5721465 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:5721465 | pubmed:pagination | 293-9 | lld:pubmed |
| pubmed-article:5721465 | pubmed:dateRevised | 2009-11-18 | lld:pubmed |
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| pubmed-article:5721465 | pubmed:meshHeading | pubmed-meshheading:5721465-... | lld:pubmed |
| pubmed-article:5721465 | pubmed:year | 1968 | lld:pubmed |
| pubmed-article:5721465 | pubmed:articleTitle | Biosynthesis of intestinal mucins. Sialic acids of sheep colonic epithelial mucin. | lld:pubmed |
| pubmed-article:5721465 | pubmed:publicationType | Journal Article | lld:pubmed |
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