| pubmed-article:56094 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:56094 | lifeskim:mentions | umls-concept:C0728866 | lld:lifeskim |
| pubmed-article:56094 | lifeskim:mentions | umls-concept:C0086418 | lld:lifeskim |
| pubmed-article:56094 | lifeskim:mentions | umls-concept:C0040223 | lld:lifeskim |
| pubmed-article:56094 | lifeskim:mentions | umls-concept:C0457405 | lld:lifeskim |
| pubmed-article:56094 | pubmed:issue | 10 | lld:pubmed |
| pubmed-article:56094 | pubmed:dateCreated | 1976-4-29 | lld:pubmed |
| pubmed-article:56094 | pubmed:abstractText | The effect of atropine, propafenone, and disopyramide on sinus node automaticity and "sino-atrial conduction" was tested in normal patients and patients with the sick sinus-syndrome. "Sino-atrial conduction time" was estimated indirectly by the extrastimulus technique. Atropine (n = 11) caused a significant increase in heart rate in all patients. The sinus node recovery time was shortened in 10 patients. "Sino-atrial conduction time" decreased on an average 35% (P less than 0.01). Three patients with a sick sinus-syndrome demonstrated a change of the pattern of the postextrasystolic pauses indicating great improvement in sino-atrial conduction. Propafenone (n = 10) led to a significant prolongation of the sinus node recovery time by 17% and of the "sino-atrial conduction time" by 27%. Disopyramide (n = 8) had no significant influence on heart rate and "sino-atrial conduction time". Sinus node recovery time was not changed in 6 patients. However, in two patients with a sick sinus-syndrome a dangerous prolongation of the sinus node recovery time after application of disopyramide occurred. The results indicate that atropine enhances sinus node function and sino-atrial conduction. On the other hand, propafenone and disopyramide exert either a depressant influence on sinus node automaticity or on sino-atrial conduction. | lld:pubmed |
| pubmed-article:56094 | pubmed:language | ger | lld:pubmed |
| pubmed-article:56094 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:56094 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:56094 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:56094 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:56094 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:56094 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:56094 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:56094 | pubmed:month | Oct | lld:pubmed |
| pubmed-article:56094 | pubmed:issn | 0300-5860 | lld:pubmed |
| pubmed-article:56094 | pubmed:author | pubmed-author:LoogenFF | lld:pubmed |
| pubmed-article:56094 | pubmed:author | pubmed-author:SeipelLL | lld:pubmed |
| pubmed-article:56094 | pubmed:author | pubmed-author:BreithardtGG | lld:pubmed |
| pubmed-article:56094 | pubmed:author | pubmed-author:BothAA | lld:pubmed |
| pubmed-article:56094 | pubmed:author | pubmed-author:HöhfeldEE | lld:pubmed |
| pubmed-article:56094 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:56094 | pubmed:volume | 64 | lld:pubmed |
| pubmed-article:56094 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:56094 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:56094 | pubmed:pagination | 895-906 | lld:pubmed |
| pubmed-article:56094 | pubmed:dateRevised | 2006-11-15 | lld:pubmed |
| pubmed-article:56094 | pubmed:meshHeading | pubmed-meshheading:56094-Hu... | lld:pubmed |
| pubmed-article:56094 | pubmed:meshHeading | pubmed-meshheading:56094-He... | lld:pubmed |
| pubmed-article:56094 | pubmed:meshHeading | pubmed-meshheading:56094-At... | lld:pubmed |
| pubmed-article:56094 | pubmed:meshHeading | pubmed-meshheading:56094-Py... | lld:pubmed |
| pubmed-article:56094 | pubmed:meshHeading | pubmed-meshheading:56094-He... | lld:pubmed |
| pubmed-article:56094 | pubmed:meshHeading | pubmed-meshheading:56094-El... | lld:pubmed |
| pubmed-article:56094 | pubmed:meshHeading | pubmed-meshheading:56094-El... | lld:pubmed |
| pubmed-article:56094 | pubmed:meshHeading | pubmed-meshheading:56094-Pr... | lld:pubmed |
| pubmed-article:56094 | pubmed:meshHeading | pubmed-meshheading:56094-Bu... | lld:pubmed |
| pubmed-article:56094 | pubmed:meshHeading | pubmed-meshheading:56094-Ti... | lld:pubmed |
| pubmed-article:56094 | pubmed:meshHeading | pubmed-meshheading:56094-Ca... | lld:pubmed |
| pubmed-article:56094 | pubmed:meshHeading | pubmed-meshheading:56094-Si... | lld:pubmed |
| pubmed-article:56094 | pubmed:meshHeading | pubmed-meshheading:56094-He... | lld:pubmed |
| pubmed-article:56094 | pubmed:meshHeading | pubmed-meshheading:56094-St... | lld:pubmed |
| pubmed-article:56094 | pubmed:meshHeading | pubmed-meshheading:56094-Di... | lld:pubmed |
| pubmed-article:56094 | pubmed:year | 1975 | lld:pubmed |
| pubmed-article:56094 | pubmed:articleTitle | [The effect of drugs on "sino-atrial conduction time" and on sinus-node automaticity in man]. | lld:pubmed |
| pubmed-article:56094 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:56094 | pubmed:publicationType | Clinical Trial | lld:pubmed |
| pubmed-article:56094 | pubmed:publicationType | English Abstract | lld:pubmed |
| pubmed-article:56094 | pubmed:publicationType | Randomized Controlled Trial | lld:pubmed |
