Statements in which the resource exists.
SubjectPredicateObjectContext
pubmed-article:537284rdf:typepubmed:Citationlld:pubmed
pubmed-article:537284lifeskim:mentionsumls-concept:C0034721lld:lifeskim
pubmed-article:537284lifeskim:mentionsumls-concept:C0034693lld:lifeskim
pubmed-article:537284lifeskim:mentionsumls-concept:C0038358lld:lifeskim
pubmed-article:537284lifeskim:mentionsumls-concept:C0001632lld:lifeskim
pubmed-article:537284lifeskim:mentionsumls-concept:C0441712lld:lifeskim
pubmed-article:537284pubmed:issue5lld:pubmed
pubmed-article:537284pubmed:dateCreated1980-5-30lld:pubmed
pubmed-article:537284pubmed:abstractTextBilateral adrenalectomy markedly aggravated gastric ulcers in rats induced by 5 or 20 mg/kg of indomethacin. The degree of aggravation was much the same in experiments done 1 and 14 days after operation. Pretreatment with prednisolone 10 mg/kg or cortisone acetate 10 mg/kg given subcutaneously significantly suppressed the aggravated ulceration in response to 20 mg/kg of indomethacin in these adrenalectomized rats. Desoxycorticosterone acetate 10 mg/kg, however, had no effect on the aggravation of indomethacin-induced ulcers. Epinephrine 0.1 or 1 mg/kg given subcutaneously markedly suppressed the indomethacin-induced ulcers in adrenalectomized rats. Removal of the adrenal medulla alone did not appreciably influence the development of indomethacin-induced ulcers. These results indicate that the adrenal cortex, particularly the area containing glucocorticoids, plays an important role in suppression of the noxious effect of indomethacin on the rat gastric mucosa.lld:pubmed
pubmed-article:537284pubmed:languageenglld:pubmed
pubmed-article:537284pubmed:journalhttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:537284pubmed:citationSubsetIMlld:pubmed
pubmed-article:537284pubmed:chemicalhttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:537284pubmed:chemicalhttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:537284pubmed:chemicalhttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:537284pubmed:chemicalhttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:537284pubmed:chemicalhttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:537284pubmed:statusMEDLINElld:pubmed
pubmed-article:537284pubmed:monthOctlld:pubmed
pubmed-article:537284pubmed:issn0021-5198lld:pubmed
pubmed-article:537284pubmed:authorpubmed-author:KasuyaYYlld:pubmed
pubmed-article:537284pubmed:authorpubmed-author:OkabeSSlld:pubmed
pubmed-article:537284pubmed:authorpubmed-author:UrushidaniTTlld:pubmed
pubmed-article:537284pubmed:issnTypePrintlld:pubmed
pubmed-article:537284pubmed:volume29lld:pubmed
pubmed-article:537284pubmed:ownerNLMlld:pubmed
pubmed-article:537284pubmed:authorsCompleteYlld:pubmed
pubmed-article:537284pubmed:pagination775-80lld:pubmed
pubmed-article:537284pubmed:dateRevised2003-11-14lld:pubmed
pubmed-article:537284pubmed:meshHeadingpubmed-meshheading:537284-A...lld:pubmed
pubmed-article:537284pubmed:meshHeadingpubmed-meshheading:537284-A...lld:pubmed
pubmed-article:537284pubmed:meshHeadingpubmed-meshheading:537284-R...lld:pubmed
pubmed-article:537284pubmed:meshHeadingpubmed-meshheading:537284-S...lld:pubmed
pubmed-article:537284pubmed:meshHeadingpubmed-meshheading:537284-D...lld:pubmed
pubmed-article:537284pubmed:meshHeadingpubmed-meshheading:537284-M...lld:pubmed
pubmed-article:537284pubmed:meshHeadingpubmed-meshheading:537284-E...lld:pubmed
pubmed-article:537284pubmed:meshHeadingpubmed-meshheading:537284-C...lld:pubmed
pubmed-article:537284pubmed:meshHeadingpubmed-meshheading:537284-A...lld:pubmed
pubmed-article:537284pubmed:meshHeadingpubmed-meshheading:537284-A...lld:pubmed
pubmed-article:537284pubmed:meshHeadingpubmed-meshheading:537284-P...lld:pubmed
pubmed-article:537284pubmed:meshHeadingpubmed-meshheading:537284-I...lld:pubmed
pubmed-article:537284pubmed:year1979lld:pubmed
pubmed-article:537284pubmed:articleTitleThe mechanism of aggravation of indomethacin-induced gastric ulcers by adrenalectomy in the rat.lld:pubmed
pubmed-article:537284pubmed:publicationTypeJournal Articlelld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:537284lld:pubmed