| pubmed-article:4598257 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:4598257 | lifeskim:mentions | umls-concept:C0332437 | lld:lifeskim |
| pubmed-article:4598257 | lifeskim:mentions | umls-concept:C0043408 | lld:lifeskim |
| pubmed-article:4598257 | lifeskim:mentions | umls-concept:C1280500 | lld:lifeskim |
| pubmed-article:4598257 | lifeskim:mentions | umls-concept:C1293097 | lld:lifeskim |
| pubmed-article:4598257 | lifeskim:mentions | umls-concept:C0596235 | lld:lifeskim |
| pubmed-article:4598257 | pubmed:issue | 6 | lld:pubmed |
| pubmed-article:4598257 | pubmed:dateCreated | 1974-7-22 | lld:pubmed |
| pubmed-article:4598257 | pubmed:abstractText | Wild-type cells of Yersinia pestis are known to exhibit a nutritional requirement for physiological levels of Ca(2+) ( approximately 2.5 mM) at 37 but not 26 C. Upon shift of Ca(2+)-deficient cultures from 26 (permissive condition) to 37 C (restrictive condition), bacterial mass quadrupled as the organisms doubled in number and then became elongated to about twice their normal size. As shown in thin sections, the resulting static cells contained axial filaments which differed from the typical irregularly lobate nucleoids of normal yersiniae grown under the permissive condition. Following prolonged cultivation under the restrictive condition (12 h), the organisms generally exhibited apparent degenerative changes, including separation or infolding of the cell wall and cytoplasmic membrane, degeneration of deoxyribonucleic acid, and appearance of vacuoles within the cytoplasm. At this time, the cells were unable to reinitiate cell division at 37 C upon addition of Ca(2+) but divided in partial synchrony after return to 26 C. This observation indicated that, at 37 C, continuous exposure to Ca(2+) is necessary for yersiniae to maintain normal morphology and the ability to divide. | lld:pubmed |
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| pubmed-article:4598257 | pubmed:language | eng | lld:pubmed |
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| pubmed-article:4598257 | pubmed:citationSubset | IM | lld:pubmed |
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| pubmed-article:4598257 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:4598257 | pubmed:month | Jun | lld:pubmed |
| pubmed-article:4598257 | pubmed:issn | 0019-9567 | lld:pubmed |
| pubmed-article:4598257 | pubmed:author | pubmed-author:HaleP APA | lld:pubmed |
| pubmed-article:4598257 | pubmed:author | pubmed-author:BrubakerR RRR | lld:pubmed |
| pubmed-article:4598257 | pubmed:author | pubmed-author:YangG CGC | lld:pubmed |
| pubmed-article:4598257 | pubmed:author | pubmed-author:LittleR VRV | lld:pubmed |
| pubmed-article:4598257 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:4598257 | pubmed:volume | 9 | lld:pubmed |
| pubmed-article:4598257 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:4598257 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:4598257 | pubmed:pagination | 1105-13 | lld:pubmed |
| pubmed-article:4598257 | pubmed:dateRevised | 2010-9-10 | lld:pubmed |
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| pubmed-article:4598257 | pubmed:year | 1974 | lld:pubmed |
| pubmed-article:4598257 | pubmed:articleTitle | Effect of Ca2+ on morphology and division of Yersinia pestis. | lld:pubmed |
| pubmed-article:4598257 | pubmed:publicationType | Journal Article | lld:pubmed |
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