| pubmed-article:4403231 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:4403231 | lifeskim:mentions | umls-concept:C0026809 | lld:lifeskim |
| pubmed-article:4403231 | lifeskim:mentions | umls-concept:C1512692 | lld:lifeskim |
| pubmed-article:4403231 | lifeskim:mentions | umls-concept:C0178539 | lld:lifeskim |
| pubmed-article:4403231 | lifeskim:mentions | umls-concept:C1704675 | lld:lifeskim |
| pubmed-article:4403231 | lifeskim:mentions | umls-concept:C0003261 | lld:lifeskim |
| pubmed-article:4403231 | lifeskim:mentions | umls-concept:C1280500 | lld:lifeskim |
| pubmed-article:4403231 | lifeskim:mentions | umls-concept:C0018134 | lld:lifeskim |
| pubmed-article:4403231 | lifeskim:mentions | umls-concept:C1546857 | lld:lifeskim |
| pubmed-article:4403231 | lifeskim:mentions | umls-concept:C2349975 | lld:lifeskim |
| pubmed-article:4403231 | lifeskim:mentions | umls-concept:C1515895 | lld:lifeskim |
| pubmed-article:4403231 | lifeskim:mentions | umls-concept:C1556066 | lld:lifeskim |
| pubmed-article:4403231 | lifeskim:mentions | umls-concept:C1619636 | lld:lifeskim |
| pubmed-article:4403231 | lifeskim:mentions | umls-concept:C1514873 | lld:lifeskim |
| pubmed-article:4403231 | lifeskim:mentions | umls-concept:C1627358 | lld:lifeskim |
| pubmed-article:4403231 | pubmed:issue | 3 | lld:pubmed |
| pubmed-article:4403231 | pubmed:dateCreated | 1972-10-2 | lld:pubmed |
| pubmed-article:4403231 | pubmed:abstractText | Experimental conditions have been established for the elicitation of an allogeneic effect on the adoptive transfer secondary anti-2,4-dinitrophenyl (DNP) antibody response in mice. Thus, spleen cells from DNP-keyhole limpet hemocyanin (KLH)-primed mice manifest good secondary anti-DNP responses to a challenge with DNP-KLH, but not with DNP-bovine gamma globulin (BGG), after adoptive transfer to irradiated syngeneic recipients. However, a good adoptive transfer secondary anti-DNP response of such cells can be elicited with DNP-BGG when a second transfer of allogeneic lymphoid cells, in appropriate numbers, is carried out 24 hr before secondary challenge. The advantage to this system is that the DNP-primed cell population as well as the population of allogeneic lymphoid cells are accessible to experimental manipulation such that the T lymphocytes of one or the other can be removed. Utilizing this model, we have established that the allogeneic effect on antibody production can operate on a population of primed B lymphocytes which have been depleted of their isologous T lymphocytes by in vitro incubation with anti-theta serum plus complement. The potential cellular interactions involved in the mechanism of this phenomenon are considered and discussed in detail. | lld:pubmed |
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| pubmed-article:4403231 | pubmed:language | eng | lld:pubmed |
| pubmed-article:4403231 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:4403231 | pubmed:citationSubset | AIM | lld:pubmed |
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| pubmed-article:4403231 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:4403231 | pubmed:month | Sep | lld:pubmed |
| pubmed-article:4403231 | pubmed:issn | 0022-1007 | lld:pubmed |
| pubmed-article:4403231 | pubmed:author | pubmed-author:LAWSJ WJW | lld:pubmed |
| pubmed-article:4403231 | pubmed:author | pubmed-author:OsborneD... | lld:pubmed |
| pubmed-article:4403231 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:4403231 | pubmed:day | 1 | lld:pubmed |
| pubmed-article:4403231 | pubmed:volume | 136 | lld:pubmed |
| pubmed-article:4403231 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:4403231 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:4403231 | pubmed:pagination | 455-65 | lld:pubmed |
| pubmed-article:4403231 | pubmed:dateRevised | 2010-6-22 | lld:pubmed |
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| pubmed-article:4403231 | pubmed:year | 1972 | lld:pubmed |
| pubmed-article:4403231 | pubmed:articleTitle | The allogeneic effect in inbred mice. II. Establishment of the cellular interactions required for enhancement of antibody production by the graft-versus-host reaction. | lld:pubmed |
| pubmed-article:4403231 | pubmed:publicationType | Journal Article | lld:pubmed |
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