pubmed-article:4058441 | rdf:type | pubmed:Citation | lld:pubmed |
pubmed-article:4058441 | lifeskim:mentions | umls-concept:C0086418 | lld:lifeskim |
pubmed-article:4058441 | lifeskim:mentions | umls-concept:C0010453 | lld:lifeskim |
pubmed-article:4058441 | lifeskim:mentions | umls-concept:C0227525 | lld:lifeskim |
pubmed-article:4058441 | lifeskim:mentions | umls-concept:C0012431 | lld:lifeskim |
pubmed-article:4058441 | lifeskim:mentions | umls-concept:C0025706 | lld:lifeskim |
pubmed-article:4058441 | lifeskim:mentions | umls-concept:C0376669 | lld:lifeskim |
pubmed-article:4058441 | lifeskim:mentions | umls-concept:C0205225 | lld:lifeskim |
pubmed-article:4058441 | pubmed:issue | 3 | lld:pubmed |
pubmed-article:4058441 | pubmed:dateCreated | 1985-12-12 | lld:pubmed |
pubmed-article:4058441 | pubmed:abstractText | The ability of N-nitrosodimethylamine (DMN) and methyl methanesulfonate (MMS) to induce DNA damage in primary cultures of human hepatocytes was examined by the alkaline elution technique. Both the agents induced a dose-dependent increase in DNA elution rate, but appreciable differences in the degree of response to the procarcinogen DMN were observed among cultures obtained from the livers of four patients. A comparative analysis of DNA fragmentation indicated a substantial similarity between human and concurrently studied rat hepatocytes in their response to both DMN and MMS. | lld:pubmed |
pubmed-article:4058441 | pubmed:language | eng | lld:pubmed |
pubmed-article:4058441 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:4058441 | pubmed:citationSubset | IM | lld:pubmed |
pubmed-article:4058441 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:4058441 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:4058441 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:4058441 | pubmed:status | MEDLINE | lld:pubmed |
pubmed-article:4058441 | pubmed:month | Nov | lld:pubmed |
pubmed-article:4058441 | pubmed:issn | 0027-5107 | lld:pubmed |
pubmed-article:4058441 | pubmed:author | pubmed-author:BrambillaGG | lld:pubmed |
pubmed-article:4058441 | pubmed:author | pubmed-author:AngeliniGG | lld:pubmed |
pubmed-article:4058441 | pubmed:author | pubmed-author:GiulianiRR | lld:pubmed |
pubmed-article:4058441 | pubmed:author | pubmed-author:MartelliAA | lld:pubmed |
pubmed-article:4058441 | pubmed:author | pubmed-author:PineKK | lld:pubmed |
pubmed-article:4058441 | pubmed:author | pubmed-author:RobbianoLL | lld:pubmed |
pubmed-article:4058441 | pubmed:issnType | Print | lld:pubmed |
pubmed-article:4058441 | pubmed:volume | 144 | lld:pubmed |
pubmed-article:4058441 | pubmed:owner | NLM | lld:pubmed |
pubmed-article:4058441 | pubmed:authorsComplete | Y | lld:pubmed |
pubmed-article:4058441 | pubmed:pagination | 209-11 | lld:pubmed |
pubmed-article:4058441 | pubmed:dateRevised | 2008-11-21 | lld:pubmed |
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pubmed-article:4058441 | pubmed:year | 1985 | lld:pubmed |
pubmed-article:4058441 | pubmed:articleTitle | DNA fragmentation by N-nitrosodimethylamine and methyl methanesulfonate in human hepatocyte primary cultures. | lld:pubmed |
pubmed-article:4058441 | pubmed:publicationType | Journal Article | lld:pubmed |
pubmed-article:4058441 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |