pubmed-article:3998215 | pubmed:abstractText | We studied the distribution of corticopontine cells in the monkey cerebral cortex. Horseradish peroxidase (HRP) was injected into the brainstem of monkeys in an attempt to fill the pontine nuclei on one or both sides. In control animals we injected the medullary pyramids or varied the route, size, or location of pontine injections. All retrograde filled corticopontine neurons were layer V pyramidal cells. Corticopontine cells were distributed within a largely continuous area of cortex which extended from the cingulate cortex medially to the sylvian fissure laterally; from the superior temporal fissure caudally to the medial part of the frontal granular cortex rostrally. Areas 4 and 6 of Brodmann (1905) contained the highest density of filled cells. In the primary visual cortex, area 17, there were a few labelled cells restricted to the rostral portion of the upper bank of the calcarine fissure, in a region representing the lower periphery of the visual field. The results are discussed in relation to the possible functions of the corticopontine system, especially the role of the extrastriate visual areas in visually guided movement. | lld:pubmed |