pubmed-article:3945172 | rdf:type | pubmed:Citation | lld:pubmed |
pubmed-article:3945172 | lifeskim:mentions | umls-concept:C0002395 | lld:lifeskim |
pubmed-article:3945172 | lifeskim:mentions | umls-concept:C0014793 | lld:lifeskim |
pubmed-article:3945172 | lifeskim:mentions | umls-concept:C0008405 | lld:lifeskim |
pubmed-article:3945172 | pubmed:issue | 6 | lld:pubmed |
pubmed-article:3945172 | pubmed:dateCreated | 1986-3-21 | lld:pubmed |
pubmed-article:3945172 | pubmed:abstractText | Choline transport and levels were studied in erythrocytes from patients with Alzheimer's disease and age-matched controls using stable isotopic tracer techniques. The mean erythrocyte choline in the Alzheimer group was 50.1 nmol ml-1 compared to 15.5 nmol ml-1 in the controls. This was significant using a Student's t test at a P of less than 0.0005. Influx of choline into the erythrocyte correlated inversely with erythrocyte choline with high significance. This study suggests that erythrocyte choline is elevated in a subset of patients with Alzheimer's disease and that the low affinity transport system is also abnormal in these patients. This abnormality of choline transport may play a role in the pathogenesis of Alzheimer's disease in some patients. | lld:pubmed |
pubmed-article:3945172 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:3945172 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:3945172 | pubmed:language | eng | lld:pubmed |
pubmed-article:3945172 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:3945172 | pubmed:citationSubset | IM | lld:pubmed |
pubmed-article:3945172 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:3945172 | pubmed:status | MEDLINE | lld:pubmed |
pubmed-article:3945172 | pubmed:month | Feb | lld:pubmed |
pubmed-article:3945172 | pubmed:issn | 0024-3205 | lld:pubmed |
pubmed-article:3945172 | pubmed:author | pubmed-author:JendenD JDJ | lld:pubmed |
pubmed-article:3945172 | pubmed:author | pubmed-author:CummingsJ LJL | lld:pubmed |
pubmed-article:3945172 | pubmed:author | pubmed-author:MillerB LBL | lld:pubmed |
pubmed-article:3945172 | pubmed:author | pubmed-author:BensonD FDF | lld:pubmed |
pubmed-article:3945172 | pubmed:author | pubmed-author:RiceKK | lld:pubmed |
pubmed-article:3945172 | pubmed:author | pubmed-author:ReadSS | lld:pubmed |
pubmed-article:3945172 | pubmed:issnType | Print | lld:pubmed |
pubmed-article:3945172 | pubmed:day | 10 | lld:pubmed |
pubmed-article:3945172 | pubmed:volume | 38 | lld:pubmed |
pubmed-article:3945172 | pubmed:owner | NLM | lld:pubmed |
pubmed-article:3945172 | pubmed:authorsComplete | Y | lld:pubmed |
pubmed-article:3945172 | pubmed:pagination | 485-90 | lld:pubmed |
pubmed-article:3945172 | pubmed:dateRevised | 2007-11-14 | lld:pubmed |
pubmed-article:3945172 | pubmed:meshHeading | pubmed-meshheading:3945172-... | lld:pubmed |
pubmed-article:3945172 | pubmed:meshHeading | pubmed-meshheading:3945172-... | lld:pubmed |
pubmed-article:3945172 | pubmed:meshHeading | pubmed-meshheading:3945172-... | lld:pubmed |
pubmed-article:3945172 | pubmed:meshHeading | pubmed-meshheading:3945172-... | lld:pubmed |
pubmed-article:3945172 | pubmed:meshHeading | pubmed-meshheading:3945172-... | lld:pubmed |
pubmed-article:3945172 | pubmed:meshHeading | pubmed-meshheading:3945172-... | lld:pubmed |
pubmed-article:3945172 | pubmed:year | 1986 | lld:pubmed |
pubmed-article:3945172 | pubmed:articleTitle | Abnormal erythrocyte choline and influx in Alzheimer's disease. | lld:pubmed |
pubmed-article:3945172 | pubmed:publicationType | Journal Article | lld:pubmed |
pubmed-article:3945172 | pubmed:publicationType | Research Support, U.S. Gov't, P.H.S. | lld:pubmed |
pubmed-article:3945172 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |