| pubmed-article:3923361 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:3923361 | lifeskim:mentions | umls-concept:C0033164 | lld:lifeskim |
| pubmed-article:3923361 | lifeskim:mentions | umls-concept:C0020792 | lld:lifeskim |
| pubmed-article:3923361 | lifeskim:mentions | umls-concept:C0006104 | lld:lifeskim |
| pubmed-article:3923361 | lifeskim:mentions | umls-concept:C0035696 | lld:lifeskim |
| pubmed-article:3923361 | lifeskim:mentions | umls-concept:C0036457 | lld:lifeskim |
| pubmed-article:3923361 | pubmed:issue | 6017 | lld:pubmed |
| pubmed-article:3923361 | pubmed:dateCreated | 1985-7-10 | lld:pubmed |
| pubmed-article:3923361 | pubmed:abstractText | To date no nucleic acid has been found in the purified infectious agent which causes the spongiform encephalopathy known as scrapie. In an attempt to identify a unique scrapie virus-associated messenger RNA in tissues of infected animals, we have synthesized an oligonucleotide probe complementary to the mRNA sequence corresponding to the amino-acid sequence of the prion protein, PrP27-30 (ref. 1). We report here that, with this probe, a complementary DNA clone representing PrP27-30 was obtained from scrapie-infected mouse brain; the DNA sequence of this clone could be translated into a protein that matches exactly the published sequence of PrP27-30. The cDNA clone hybridized to a single 2.4-2.5-kilobase (kb) mRNA from both normal and scrapie-infected brain. Thus, the PrP27-30 mRNA is not uniquely associated with scrapie infectivity, suggesting that PrP27-30 may be a normal component of mouse and hamster brain. | lld:pubmed |
| pubmed-article:3923361 | pubmed:language | eng | lld:pubmed |
| pubmed-article:3923361 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:3923361 | pubmed:citationSubset | IM | lld:pubmed |
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| pubmed-article:3923361 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:3923361 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:3923361 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:3923361 | pubmed:issn | 0028-0836 | lld:pubmed |
| pubmed-article:3923361 | pubmed:author | pubmed-author:MayerLL | lld:pubmed |
| pubmed-article:3923361 | pubmed:author | pubmed-author:ChesebroBB | lld:pubmed |
| pubmed-article:3923361 | pubmed:author | pubmed-author:NishioJJ | lld:pubmed |
| pubmed-article:3923361 | pubmed:author | pubmed-author:WehrlyKK | lld:pubmed |
| pubmed-article:3923361 | pubmed:author | pubmed-author:BloomMM | lld:pubmed |
| pubmed-article:3923361 | pubmed:author | pubmed-author:LechnerDD | lld:pubmed |
| pubmed-article:3923361 | pubmed:author | pubmed-author:KeithJ MJM | lld:pubmed |
| pubmed-article:3923361 | pubmed:author | pubmed-author:RaceRR | lld:pubmed |
| pubmed-article:3923361 | pubmed:author | pubmed-author:BergstromSS | lld:pubmed |
| pubmed-article:3923361 | pubmed:author | pubmed-author:RobbinsKK | lld:pubmed |
| pubmed-article:3923361 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:3923361 | pubmed:volume | 315 | lld:pubmed |
| pubmed-article:3923361 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:3923361 | pubmed:authorsComplete | N | lld:pubmed |
| pubmed-article:3923361 | pubmed:pagination | 331-3 | lld:pubmed |
| pubmed-article:3923361 | pubmed:dateRevised | 2005-11-17 | lld:pubmed |
| pubmed-article:3923361 | pubmed:meshHeading | pubmed-meshheading:3923361-... | lld:pubmed |
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| pubmed-article:3923361 | pubmed:meshHeading | pubmed-meshheading:3923361-... | lld:pubmed |
| pubmed-article:3923361 | pubmed:articleTitle | Identification of scrapie prion protein-specific mRNA in scrapie-infected and uninfected brain. | lld:pubmed |
| pubmed-article:3923361 | pubmed:publicationType | Journal Article | lld:pubmed |
| entrez-gene:19122 | entrezgene:pubmed | pubmed-article:3923361 | lld:entrezgene |
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