| pubmed-article:3919107 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:3919107 | lifeskim:mentions | umls-concept:C0039005 | lld:lifeskim |
| pubmed-article:3919107 | lifeskim:mentions | umls-concept:C0242275 | lld:lifeskim |
| pubmed-article:3919107 | lifeskim:mentions | umls-concept:C0014520 | lld:lifeskim |
| pubmed-article:3919107 | lifeskim:mentions | umls-concept:C0003695 | lld:lifeskim |
| pubmed-article:3919107 | lifeskim:mentions | umls-concept:C0030685 | lld:lifeskim |
| pubmed-article:3919107 | lifeskim:mentions | umls-concept:C0680255 | lld:lifeskim |
| pubmed-article:3919107 | lifeskim:mentions | umls-concept:C0391871 | lld:lifeskim |
| pubmed-article:3919107 | lifeskim:mentions | umls-concept:C1283071 | lld:lifeskim |
| pubmed-article:3919107 | lifeskim:mentions | umls-concept:C1963578 | lld:lifeskim |
| pubmed-article:3919107 | pubmed:issue | 3 | lld:pubmed |
| pubmed-article:3919107 | pubmed:dateCreated | 1985-4-8 | lld:pubmed |
| pubmed-article:3919107 | pubmed:abstractText | Epidermal growth factor (EGF) at physiologic concentrations (0.001-0.1 microgram/ml) stimulated the release of [14C] arachidonic acid [14C-AA] from pig epidermis. Although EGF stimulated the release of AA in the absence of exogenously added calcium to some extent, the addition of calcium (0.3-1.2 mM) significantly potentiated the release of AA stimulated by EGF. Ionophore A23187, which is known to stimulate phospholipase A2 activity by opening the calcium gates, potentiated the EGF-stimulated release of AA. The stimulatory effect of EGF was partially inhibited by the addition of mepacrine (70% inhibition at 10 microM) and by the pretreatment of hydrocortisone (60% inhibition at 1.0 microM). The loss of 14C-labeled phospholipids in pig epidermis was mainly due to the degradation of 14C-labeled phosphatidylcholine. Present results and recent reports by other workers suggest that EGF stimulates phospholipase A2 activity and result in the increased release of AA. | lld:pubmed |
| pubmed-article:3919107 | pubmed:language | eng | lld:pubmed |
| pubmed-article:3919107 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:3919107 | pubmed:citationSubset | IM | lld:pubmed |
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| pubmed-article:3919107 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
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| pubmed-article:3919107 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:3919107 | pubmed:month | Mar | lld:pubmed |
| pubmed-article:3919107 | pubmed:issn | 0022-202X | lld:pubmed |
| pubmed-article:3919107 | pubmed:author | pubmed-author:MiuraYY | lld:pubmed |
| pubmed-article:3919107 | pubmed:author | pubmed-author:AoyagiTT | lld:pubmed |
| pubmed-article:3919107 | pubmed:author | pubmed-author:KatoNN | lld:pubmed |
| pubmed-article:3919107 | pubmed:author | pubmed-author:KobayashiHH | lld:pubmed |
| pubmed-article:3919107 | pubmed:author | pubmed-author:SuyaHH | lld:pubmed |
| pubmed-article:3919107 | pubmed:author | pubmed-author:NemotoOO | lld:pubmed |
| pubmed-article:3919107 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:3919107 | pubmed:volume | 84 | lld:pubmed |
| pubmed-article:3919107 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:3919107 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:3919107 | pubmed:pagination | 168-71 | lld:pubmed |
| pubmed-article:3919107 | pubmed:dateRevised | 2007-11-15 | lld:pubmed |
| pubmed-article:3919107 | pubmed:meshHeading | pubmed-meshheading:3919107-... | lld:pubmed |
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| pubmed-article:3919107 | pubmed:meshHeading | pubmed-meshheading:3919107-... | lld:pubmed |
| pubmed-article:3919107 | pubmed:meshHeading | pubmed-meshheading:3919107-... | lld:pubmed |
| pubmed-article:3919107 | pubmed:meshHeading | pubmed-meshheading:3919107-... | lld:pubmed |
| pubmed-article:3919107 | pubmed:meshHeading | pubmed-meshheading:3919107-... | lld:pubmed |
| pubmed-article:3919107 | pubmed:year | 1985 | lld:pubmed |
| pubmed-article:3919107 | pubmed:articleTitle | Epidermal growth factor stimulates release of arachidonic acid in pig epidermis. | lld:pubmed |
| pubmed-article:3919107 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:3919107 | pubmed:publicationType | In Vitro | lld:pubmed |
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