| pubmed-article:3918594 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:3918594 | lifeskim:mentions | umls-concept:C0023449 | lld:lifeskim |
| pubmed-article:3918594 | lifeskim:mentions | umls-concept:C0039194 | lld:lifeskim |
| pubmed-article:3918594 | lifeskim:mentions | umls-concept:C0017351 | lld:lifeskim |
| pubmed-article:3918594 | lifeskim:mentions | umls-concept:C1511695 | lld:lifeskim |
| pubmed-article:3918594 | pubmed:issue | 3 | lld:pubmed |
| pubmed-article:3918594 | pubmed:dateCreated | 1985-4-15 | lld:pubmed |
| pubmed-article:3918594 | pubmed:abstractText | We studied the arrangement of the immunoglobulin heavy chain genes by Southern blot analysis of DNA freshly obtained from marrow blast cells of 14 children with T cell acute lymphoblastic leukemia (T-ALL) using probes to the C mu and JH gene segments: At least one of the C mu-gene alleles was rearranged in three cases. In two of these, one C mu gene had the germ-line configuration and one was rearranged, whereas both alleles were rearranged in the third case. In one case, a rearranged heavy chain gene hybridized to the C mu-region probe, but not to the JH probe, indicating that the entire JH region had been deleted. These results demonstrate that immunoglobulin heavy chain gene rearrangements are not restricted to B lineage lymphoproliferative diseases in humans. | lld:pubmed |
| pubmed-article:3918594 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:3918594 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:3918594 | pubmed:language | eng | lld:pubmed |
| pubmed-article:3918594 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:3918594 | pubmed:citationSubset | AIM | lld:pubmed |
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| pubmed-article:3918594 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:3918594 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:3918594 | pubmed:month | Mar | lld:pubmed |
| pubmed-article:3918594 | pubmed:issn | 0006-4971 | lld:pubmed |
| pubmed-article:3918594 | pubmed:author | pubmed-author:MauerA MAM | lld:pubmed |
| pubmed-article:3918594 | pubmed:author | pubmed-author:RovigattiUU | lld:pubmed |
| pubmed-article:3918594 | pubmed:author | pubmed-author:MurphyS BSB | lld:pubmed |
| pubmed-article:3918594 | pubmed:author | pubmed-author:KitchingmanG... | lld:pubmed |
| pubmed-article:3918594 | pubmed:author | pubmed-author:StassSS | lld:pubmed |
| pubmed-article:3918594 | pubmed:author | pubmed-author:MelvinSS | lld:pubmed |
| pubmed-article:3918594 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:3918594 | pubmed:volume | 65 | lld:pubmed |
| pubmed-article:3918594 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:3918594 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:3918594 | pubmed:pagination | 725-9 | lld:pubmed |
| pubmed-article:3918594 | pubmed:dateRevised | 2007-11-15 | lld:pubmed |
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| pubmed-article:3918594 | pubmed:year | 1985 | lld:pubmed |
| pubmed-article:3918594 | pubmed:articleTitle | Rearrangement of immunoglobulin heavy chain genes in T cell acute lymphoblastic leukemia. | lld:pubmed |
| pubmed-article:3918594 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:3918594 | pubmed:publicationType | Research Support, U.S. Gov't, P.H.S. | lld:pubmed |
| pubmed-article:3918594 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
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