| pubmed-article:3891756 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:3891756 | lifeskim:mentions | umls-concept:C2717874 | lld:lifeskim |
| pubmed-article:3891756 | lifeskim:mentions | umls-concept:C0080194 | lld:lifeskim |
| pubmed-article:3891756 | lifeskim:mentions | umls-concept:C0017978 | lld:lifeskim |
| pubmed-article:3891756 | lifeskim:mentions | umls-concept:C1167622 | lld:lifeskim |
| pubmed-article:3891756 | lifeskim:mentions | umls-concept:C2003941 | lld:lifeskim |
| pubmed-article:3891756 | lifeskim:mentions | umls-concept:C0037791 | lld:lifeskim |
| pubmed-article:3891756 | lifeskim:mentions | umls-concept:C0560013 | lld:lifeskim |
| pubmed-article:3891756 | pubmed:issue | 14 | lld:pubmed |
| pubmed-article:3891756 | pubmed:dateCreated | 1985-8-16 | lld:pubmed |
| pubmed-article:3891756 | pubmed:abstractText | A strain of Escherichia coli originally isolated from urine of a patient with acute pyelonephritis was studied in detail for binding to glycosphingolipids. Bacteria labeled metabolically with [14C]glucose were layered over a glycolipid chromatogram and bound bacteria were detected by autoradiography. The detection was down to a few ng of glycolipid (pmol level) under these assay conditions. At a test level of 500 ng all glycolipids (more than a dozen molecular species analyzed) with Gal alpha 1----4Gal as an internal or terminal part bound the bacteria strongly while glycolipids known to lack this sequence were negative. Conformational analysis using hard sphere calculations including the exo-anomeric effect showed a bend in the saccharide chain at this disaccharide with a largely hydrophobic surface of the convex side, probably being part of the binding epitope. Mixtures of glycolipids isolated from a human ureter scraping and from urinary sediments bound bacteria in the 2- to 7-sugar interval. Thus, this infectious strain of E. coli recognizes glycolipids being present in epithelial cells lining the urinary tract. | lld:pubmed |
| pubmed-article:3891756 | pubmed:language | eng | lld:pubmed |
| pubmed-article:3891756 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:3891756 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:3891756 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
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| pubmed-article:3891756 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:3891756 | pubmed:month | Jul | lld:pubmed |
| pubmed-article:3891756 | pubmed:issn | 0021-9258 | lld:pubmed |
| pubmed-article:3891756 | pubmed:author | pubmed-author:BockKK | lld:pubmed |
| pubmed-article:3891756 | pubmed:author | pubmed-author:KarlssonK AKA | lld:pubmed |
| pubmed-article:3891756 | pubmed:author | pubmed-author:SamuelssonB... | lld:pubmed |
| pubmed-article:3891756 | pubmed:author | pubmed-author:LefflerHH | lld:pubmed |
| pubmed-article:3891756 | pubmed:author | pubmed-author:EdénC SCS | lld:pubmed |
| pubmed-article:3891756 | pubmed:author | pubmed-author:HanssonG CGC | lld:pubmed |
| pubmed-article:3891756 | pubmed:author | pubmed-author:BreimerM EME | lld:pubmed |
| pubmed-article:3891756 | pubmed:author | pubmed-author:LarsonGG | lld:pubmed |
| pubmed-article:3891756 | pubmed:author | pubmed-author:StrömbergNN | lld:pubmed |
| pubmed-article:3891756 | pubmed:author | pubmed-author:BrignoleAA | lld:pubmed |
| pubmed-article:3891756 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:3891756 | pubmed:day | 15 | lld:pubmed |
| pubmed-article:3891756 | pubmed:volume | 260 | lld:pubmed |
| pubmed-article:3891756 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:3891756 | pubmed:authorsComplete | N | lld:pubmed |
| pubmed-article:3891756 | pubmed:pagination | 8545-51 | lld:pubmed |
| pubmed-article:3891756 | pubmed:dateRevised | 2006-11-15 | lld:pubmed |
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| pubmed-article:3891756 | pubmed:year | 1985 | lld:pubmed |
| pubmed-article:3891756 | pubmed:articleTitle | Specificity of binding of a strain of uropathogenic Escherichia coli to Gal alpha 1----4Gal-containing glycosphingolipids. | lld:pubmed |
| pubmed-article:3891756 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:3891756 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
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