| pubmed-article:3814829 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:3814829 | lifeskim:mentions | umls-concept:C0021311 | lld:lifeskim |
| pubmed-article:3814829 | lifeskim:mentions | umls-concept:C0030705 | lld:lifeskim |
| pubmed-article:3814829 | lifeskim:mentions | umls-concept:C0014792 | lld:lifeskim |
| pubmed-article:3814829 | lifeskim:mentions | umls-concept:C0019054 | lld:lifeskim |
| pubmed-article:3814829 | lifeskim:mentions | umls-concept:C0205082 | lld:lifeskim |
| pubmed-article:3814829 | lifeskim:mentions | umls-concept:C0086476 | lld:lifeskim |
| pubmed-article:3814829 | pubmed:issue | 2 | lld:pubmed |
| pubmed-article:3814829 | pubmed:dateCreated | 1987-3-30 | lld:pubmed |
| pubmed-article:3814829 | pubmed:abstractText | The exposure of Thomsen-Friedenreich (T) antigens on RBCs, serum neuraminidase, and serum hemoglobin levels were investigated in 53 adult surgical intensive care unit (ICU) patients with septicemia. Unmasked T-antigens were assayed by a hemagglutination test using peanut agglutinin (PNA) (direct anti-T test), and by an indirect anti-T test employing rabbit anti-PNA globulin. RBC T-activation was demonstrated in 17/53 patients (32%); in 2/53 patients (4%) the direct anti-T test was positive, indicating strong T-exposure. No polyagglutination phenomena were observed. Serum neuraminidase was elevated in 12/17 (71%) patients with T-activation and in 7/36 (19%) patients without T-activation. Free serum hemoglobin was elevated in 12/17 (71%) patients with T-activation and in 5/36 (14%) patients without T-activation. Correlations between T-activation and serum neuraminidase and between T-activation and serum hemoglobin were significant (p less than 0.001). Potentially neuraminidase-releasing bacteria were demonstrated in 13/17 (76%) patients with RBC T-exposure. We conclude that neuraminidase-induced RBC T-activation and subsequent hemolysis may be involved in the pathomechanism of hemolytic anemia in patients with severe infections. | lld:pubmed |
| pubmed-article:3814829 | pubmed:language | eng | lld:pubmed |
| pubmed-article:3814829 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:3814829 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:3814829 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:3814829 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:3814829 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:3814829 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:3814829 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:3814829 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:3814829 | pubmed:month | Feb | lld:pubmed |
| pubmed-article:3814829 | pubmed:issn | 0006-5242 | lld:pubmed |
| pubmed-article:3814829 | pubmed:author | pubmed-author:HellerWW | lld:pubmed |
| pubmed-article:3814829 | pubmed:author | pubmed-author:LenzGG | lld:pubmed |
| pubmed-article:3814829 | pubmed:author | pubmed-author:CASEYH WHW | lld:pubmed |
| pubmed-article:3814829 | pubmed:author | pubmed-author:SugiSS | lld:pubmed |
| pubmed-article:3814829 | pubmed:author | pubmed-author:GoesUU | lld:pubmed |
| pubmed-article:3814829 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:3814829 | pubmed:volume | 54 | lld:pubmed |
| pubmed-article:3814829 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:3814829 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:3814829 | pubmed:pagination | 89-96 | lld:pubmed |
| pubmed-article:3814829 | pubmed:dateRevised | 2007-12-5 | lld:pubmed |
| pubmed-article:3814829 | pubmed:meshHeading | pubmed-meshheading:3814829-... | lld:pubmed |
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| pubmed-article:3814829 | pubmed:meshHeading | pubmed-meshheading:3814829-... | lld:pubmed |
| pubmed-article:3814829 | pubmed:meshHeading | pubmed-meshheading:3814829-... | lld:pubmed |
| pubmed-article:3814829 | pubmed:meshHeading | pubmed-meshheading:3814829-... | lld:pubmed |
| pubmed-article:3814829 | pubmed:meshHeading | pubmed-meshheading:3814829-... | lld:pubmed |
| pubmed-article:3814829 | pubmed:meshHeading | pubmed-meshheading:3814829-... | lld:pubmed |
| pubmed-article:3814829 | pubmed:year | 1987 | lld:pubmed |
| pubmed-article:3814829 | pubmed:articleTitle | Red blood cell T-activation and hemolysis in surgical intensive care patients with severe infections. | lld:pubmed |
| pubmed-article:3814829 | pubmed:publicationType | Journal Article | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:3814829 | lld:pubmed |
