| pubmed-article:3797428 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:3797428 | lifeskim:mentions | umls-concept:C0035222 | lld:lifeskim |
| pubmed-article:3797428 | lifeskim:mentions | umls-concept:C0033684 | lld:lifeskim |
| pubmed-article:3797428 | lifeskim:mentions | umls-concept:C0022100 | lld:lifeskim |
| pubmed-article:3797428 | lifeskim:mentions | umls-concept:C0936012 | lld:lifeskim |
| pubmed-article:3797428 | lifeskim:mentions | umls-concept:C0205203 | lld:lifeskim |
| pubmed-article:3797428 | pubmed:issue | 1 | lld:pubmed |
| pubmed-article:3797428 | pubmed:dateCreated | 1987-2-10 | lld:pubmed |
| pubmed-article:3797428 | pubmed:abstractText | Serum proteins in normal and ARDS bronchoalveolar lavages were analyzed using crossed immunoelectrophoresis. Normal lavages demonstrated relatively few proteins (albumin, alpha 1-antitrypsin, transferrin, and haptoglobin) in low concentrations. In contrast, substantial amounts of all identifiable serum proteins were detected in ARDS lavages. IgA was apparently locally produced. Two of the largest proteins, beta-lipoprotein (mol wt greater than 2 million) and IgM (mol wt approximately 900,000) were found to be complexed as evidenced by their coprecipitation in a single spike in ARDS lavage. Electrophoretic modifications of ARDS albumin and alpha 1-antitrypsin precipitation peaks and partial identity spurring of the alpha 1-lipoprotein peak with other precipitation loops indicated possible complex formation between these proteins and other possibly pathogenic lung fluid constituents. Similarly, modifications of orosomucoid and Gc-globulin peaks indicated possible molecular alterations resulting from interactions with other components. The relatively few protein modifications exhibited in ARDS lavages together with alpha 1-antitrypsin-protease complex formation confirm the relative absence of substantial proteolytic activity in ARDS edema fluids obtained within 12 hr of the onset of the syndrome demonstrated in previous studies. | lld:pubmed |
| pubmed-article:3797428 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:3797428 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:3797428 | pubmed:language | eng | lld:pubmed |
| pubmed-article:3797428 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:3797428 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:3797428 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:3797428 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:3797428 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:3797428 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:3797428 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:3797428 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:3797428 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:3797428 | pubmed:month | Jan | lld:pubmed |
| pubmed-article:3797428 | pubmed:issn | 0037-9727 | lld:pubmed |
| pubmed-article:3797428 | pubmed:author | pubmed-author:HyersT MTM | lld:pubmed |
| pubmed-article:3797428 | pubmed:author | pubmed-author:CrowleA JAJ | lld:pubmed |
| pubmed-article:3797428 | pubmed:author | pubmed-author:EmmettMM | lld:pubmed |
| pubmed-article:3797428 | pubmed:author | pubmed-author:FowlerA AAA | lld:pubmed |
| pubmed-article:3797428 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:3797428 | pubmed:volume | 184 | lld:pubmed |
| pubmed-article:3797428 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:3797428 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:3797428 | pubmed:pagination | 83-91 | lld:pubmed |
| pubmed-article:3797428 | pubmed:dateRevised | 2007-11-14 | lld:pubmed |
| pubmed-article:3797428 | pubmed:meshHeading | pubmed-meshheading:3797428-... | lld:pubmed |
| pubmed-article:3797428 | pubmed:meshHeading | pubmed-meshheading:3797428-... | lld:pubmed |
| pubmed-article:3797428 | pubmed:meshHeading | pubmed-meshheading:3797428-... | lld:pubmed |
| pubmed-article:3797428 | pubmed:meshHeading | pubmed-meshheading:3797428-... | lld:pubmed |
| pubmed-article:3797428 | pubmed:meshHeading | pubmed-meshheading:3797428-... | lld:pubmed |
| pubmed-article:3797428 | pubmed:meshHeading | pubmed-meshheading:3797428-... | lld:pubmed |
| pubmed-article:3797428 | pubmed:meshHeading | pubmed-meshheading:3797428-... | lld:pubmed |
| pubmed-article:3797428 | pubmed:meshHeading | pubmed-meshheading:3797428-... | lld:pubmed |
| pubmed-article:3797428 | pubmed:meshHeading | pubmed-meshheading:3797428-... | lld:pubmed |
| pubmed-article:3797428 | pubmed:meshHeading | pubmed-meshheading:3797428-... | lld:pubmed |
| pubmed-article:3797428 | pubmed:meshHeading | pubmed-meshheading:3797428-... | lld:pubmed |
| pubmed-article:3797428 | pubmed:meshHeading | pubmed-meshheading:3797428-... | lld:pubmed |
| pubmed-article:3797428 | pubmed:year | 1987 | lld:pubmed |
| pubmed-article:3797428 | pubmed:articleTitle | Crossed immunoelectrophoretic analysis of ARDS lavage proteins. | lld:pubmed |
| pubmed-article:3797428 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:3797428 | pubmed:publicationType | Research Support, U.S. Gov't, P.H.S. | lld:pubmed |
| pubmed-article:3797428 | pubmed:publicationType | Research Support, U.S. Gov't, Non-P.H.S. | lld:pubmed |
| pubmed-article:3797428 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:3797428 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:3797428 | lld:pubmed |
