pubmed-article:3792669 | rdf:type | pubmed:Citation | lld:pubmed |
pubmed-article:3792669 | lifeskim:mentions | umls-concept:C0030705 | lld:lifeskim |
pubmed-article:3792669 | lifeskim:mentions | umls-concept:C0019638 | lld:lifeskim |
pubmed-article:3792669 | lifeskim:mentions | umls-concept:C0026724 | lld:lifeskim |
pubmed-article:3792669 | lifeskim:mentions | umls-concept:C0013295 | lld:lifeskim |
pubmed-article:3792669 | lifeskim:mentions | umls-concept:C0043515 | lld:lifeskim |
pubmed-article:3792669 | lifeskim:mentions | umls-concept:C0683278 | lld:lifeskim |
pubmed-article:3792669 | pubmed:dateCreated | 1987-2-19 | lld:pubmed |
pubmed-article:3792669 | pubmed:abstractText | Endoscopic biopsies were taken from the oxyntic mucosa in patients with duodenal ulcer (DU) before and after 4 weeks of treatment with omeprazole. Biopsies were also obtained from Zollinger-Ellison (ZE) patients before and during treatment with omeprazole; these patients had previously failed to respond to other therapies aiming at reducing gastric acid secretion. Healthy volunteers served as controls. Light-microscopic studies of biopsy sections revealed superficial gastritis in most of the patients. Endocrine cell volume density (that is, the percentage of mucosal volume occupied by endocrine cells) was 0.3% in the DU patients and 0.7% in the ZE patients before omeprazole treatment. No significant change occurred during omeprazole treatment, which in the ZE patients continued for up to 21 months. In the controls, 0.3% of the mucosal volume was occupied by endocrine cells. Parietal cell volume density was about 15% in both the DU patients and in the controls; in the ZE patients, slightly but not significantly higher values were recorded. No significant change was observed during omeprazole treatment. | lld:pubmed |
pubmed-article:3792669 | pubmed:language | eng | lld:pubmed |
pubmed-article:3792669 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:3792669 | pubmed:citationSubset | IM | lld:pubmed |
pubmed-article:3792669 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:3792669 | pubmed:status | MEDLINE | lld:pubmed |
pubmed-article:3792669 | pubmed:issn | 0012-2823 | lld:pubmed |
pubmed-article:3792669 | pubmed:author | pubmed-author:HelanderH FHF | lld:pubmed |
pubmed-article:3792669 | pubmed:issnType | Print | lld:pubmed |
pubmed-article:3792669 | pubmed:volume | 35 Suppl 1 | lld:pubmed |
pubmed-article:3792669 | pubmed:owner | NLM | lld:pubmed |
pubmed-article:3792669 | pubmed:authorsComplete | Y | lld:pubmed |
pubmed-article:3792669 | pubmed:pagination | 123-9 | lld:pubmed |
pubmed-article:3792669 | pubmed:dateRevised | 2004-11-17 | lld:pubmed |
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pubmed-article:3792669 | pubmed:year | 1986 | lld:pubmed |
pubmed-article:3792669 | pubmed:articleTitle | Oxyntic mucosa histology in omeprazole-treated patients suffering from duodenal ulcer or Zollinger-Ellison syndrome. | lld:pubmed |
pubmed-article:3792669 | pubmed:publicationType | Journal Article | lld:pubmed |
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