| pubmed-article:3772297 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:3772297 | lifeskim:mentions | umls-concept:C0086418 | lld:lifeskim |
| pubmed-article:3772297 | lifeskim:mentions | umls-concept:C0330390 | lld:lifeskim |
| pubmed-article:3772297 | lifeskim:mentions | umls-concept:C0017337 | lld:lifeskim |
| pubmed-article:3772297 | lifeskim:mentions | umls-concept:C0936012 | lld:lifeskim |
| pubmed-article:3772297 | lifeskim:mentions | umls-concept:C1711207 | lld:lifeskim |
| pubmed-article:3772297 | pubmed:issue | 5 | lld:pubmed |
| pubmed-article:3772297 | pubmed:dateCreated | 1986-12-3 | lld:pubmed |
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| pubmed-article:3772297 | pubmed:abstractText | We have isolated and sequenced five germline V beta gene segments that are homologous to the V region of the YT35 cDNA encoding the beta chain of the T cell antigen receptor from the tumor MOLT-3. One of these gene segments is identical to the YT35 V segment, and therefore is the corresponding germline V beta gene segment encoding the YT35 cDNA. The other four V beta members exhibit 77-98% homology to the YT35 V gene segment. Two of these V beta gene segments are pseudogenes. Analyses of the coding region sequences reveal that, although the V beta segments are very diverse, they are mutating at a rate comparable to that observed in most eukaryotic genes. Analyses of the genomic clones show that the spacing distance between germline V beta gene segments ranges from 3 kb to greater than 30 kb, and the entire V beta 8 subfamily appears to be linked by a total of no more than 110 kb of DNA. | lld:pubmed |
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| pubmed-article:3772297 | pubmed:language | eng | lld:pubmed |
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| pubmed-article:3772297 | pubmed:citationSubset | IM | lld:pubmed |
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| pubmed-article:3772297 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:3772297 | pubmed:month | Nov | lld:pubmed |
| pubmed-article:3772297 | pubmed:issn | 0022-1007 | lld:pubmed |
| pubmed-article:3772297 | pubmed:author | pubmed-author:HoodL ELE | lld:pubmed |
| pubmed-article:3772297 | pubmed:author | pubmed-author:LalFF | lld:pubmed |
| pubmed-article:3772297 | pubmed:author | pubmed-author:SilNN | lld:pubmed |
| pubmed-article:3772297 | pubmed:author | pubmed-author:StraussE CEC | lld:pubmed |
| pubmed-article:3772297 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:3772297 | pubmed:day | 1 | lld:pubmed |
| pubmed-article:3772297 | pubmed:volume | 164 | lld:pubmed |
| pubmed-article:3772297 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:3772297 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:3772297 | pubmed:pagination | 1600-14 | lld:pubmed |
| pubmed-article:3772297 | pubmed:dateRevised | 2010-11-18 | lld:pubmed |
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| pubmed-article:3772297 | pubmed:year | 1986 | lld:pubmed |
| pubmed-article:3772297 | pubmed:articleTitle | Analysis of a human V beta gene subfamily. | lld:pubmed |
| pubmed-article:3772297 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:3772297 | pubmed:publicationType | Research Support, U.S. Gov't, P.H.S. | lld:pubmed |
| pubmed-article:3772297 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
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