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pubmed-article:377134pubmed:abstractTextEight patients were treated concurrently with a constant dose of phenytoin and valproic acid for 1 year. During initial therapy with valproic acid, total plasma phenytoin levels decreased. The interaction was transient and was not observed at the end of 1 year. Total plasma phenytoin levels returned to pre-valproic-acid levels in seven patients.lld:pubmed
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pubmed-article:377134pubmed:articleTitleValproic acid and plasma levels of phenytoin.lld:pubmed
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