| pubmed-article:3717953 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:3717953 | lifeskim:mentions | umls-concept:C0332441 | lld:lifeskim |
| pubmed-article:3717953 | lifeskim:mentions | umls-concept:C0033681 | lld:lifeskim |
| pubmed-article:3717953 | lifeskim:mentions | umls-concept:C0728938 | lld:lifeskim |
| pubmed-article:3717953 | lifeskim:mentions | umls-concept:C1998793 | lld:lifeskim |
| pubmed-article:3717953 | lifeskim:mentions | umls-concept:C1880022 | lld:lifeskim |
| pubmed-article:3717953 | pubmed:issue | 2 | lld:pubmed |
| pubmed-article:3717953 | pubmed:dateCreated | 1986-6-30 | lld:pubmed |
| pubmed-article:3717953 | pubmed:abstractText | Three membranous protein tyrosine kinases (PTKs) have been partially purified from human placenta and pig brain. The two placental enzymes (PTK-1 and -2) are distinct with respect to solubility in detergents, molecular weight, and enzymatic properties. The brain protein tyrosine kinase resembles placental PTK-1 with respect to molecular weight and some kinetic properties. However, stimulation of brain PTK is greater with Mn2+ than with Mg2+ whereas placental PTK-1 gives higher rates with Mg2+ than with Mn2+. All three enzymes are inhibited about 50% by 0.1 M NaCl. A monoclonal antibody raised in vitro against the brain enzyme inhibits brain PTK as well as placental PTK-2, but has no effect against PTK-1 or pp60src. It thus appears that these three enzymes are distinct entities that differ from each other both kinetically and immunologically. With synthetic tyrosine-glutamic acid polymers as a substrate, protein tyrosine kinase activity can be detected in crude extracts of membranes. | lld:pubmed |
| pubmed-article:3717953 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:3717953 | pubmed:language | eng | lld:pubmed |
| pubmed-article:3717953 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:3717953 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:3717953 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:3717953 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:3717953 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
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| pubmed-article:3717953 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:3717953 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:3717953 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:3717953 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:3717953 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:3717953 | pubmed:month | Jun | lld:pubmed |
| pubmed-article:3717953 | pubmed:issn | 0003-9861 | lld:pubmed |
| pubmed-article:3717953 | pubmed:author | pubmed-author:RackerEE | lld:pubmed |
| pubmed-article:3717953 | pubmed:author | pubmed-author:BraunSS | lld:pubmed |
| pubmed-article:3717953 | pubmed:author | pubmed-author:LettieriJ AJA | lld:pubmed |
| pubmed-article:3717953 | pubmed:author | pubmed-author:Abdel GhanyMM | lld:pubmed |
| pubmed-article:3717953 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:3717953 | pubmed:volume | 247 | lld:pubmed |
| pubmed-article:3717953 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:3717953 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:3717953 | pubmed:pagination | 424-32 | lld:pubmed |
| pubmed-article:3717953 | pubmed:dateRevised | 2009-11-19 | lld:pubmed |
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| pubmed-article:3717953 | pubmed:meshHeading | pubmed-meshheading:3717953-... | lld:pubmed |
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| pubmed-article:3717953 | pubmed:meshHeading | pubmed-meshheading:3717953-... | lld:pubmed |
| pubmed-article:3717953 | pubmed:year | 1986 | lld:pubmed |
| pubmed-article:3717953 | pubmed:articleTitle | Partial purification and characterization of protein tyrosine kinases from normal tissues. | lld:pubmed |
| pubmed-article:3717953 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:3717953 | pubmed:publicationType | Research Support, U.S. Gov't, P.H.S. | lld:pubmed |
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