| pubmed-article:3663263 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:3663263 | lifeskim:mentions | umls-concept:C0003873 | lld:lifeskim |
| pubmed-article:3663263 | lifeskim:mentions | umls-concept:C0023516 | lld:lifeskim |
| pubmed-article:3663263 | lifeskim:mentions | umls-concept:C0016157 | lld:lifeskim |
| pubmed-article:3663263 | lifeskim:mentions | umls-concept:C0542341 | lld:lifeskim |
| pubmed-article:3663263 | lifeskim:mentions | umls-concept:C1280500 | lld:lifeskim |
| pubmed-article:3663263 | lifeskim:mentions | umls-concept:C0242297 | lld:lifeskim |
| pubmed-article:3663263 | lifeskim:mentions | umls-concept:C0079411 | lld:lifeskim |
| pubmed-article:3663263 | lifeskim:mentions | umls-concept:C0599745 | lld:lifeskim |
| pubmed-article:3663263 | pubmed:issue | 9 | lld:pubmed |
| pubmed-article:3663263 | pubmed:dateCreated | 1987-11-4 | lld:pubmed |
| pubmed-article:3663263 | pubmed:abstractText | Twelve patients with active rheumatoid arthritis supplemented their usual diet with 20 gm of Max-EPA fish oil, daily, for 6 weeks. Following this supplementation, the ratio of arachidonic acid to eicosapentaenoic acid in the patients' neutrophil cellular lipids decreased from 81:1 to 2.7:1, and the mean generation of leukotriene B4 (with calcium ionophore stimulation) significantly declined by 33%. The mean neutrophil chemotaxis to both leukotriene B4 and FMLP significantly increased toward the normal range at week 6. The generation of 5-lipoxygenase products by calcium ionophore-stimulated monocytes was not significantly suppressed, but a significant decline (37%) in platelet-activating factor generation was noted at week 6. The modulation of these measures of leukocyte inflammatory potential suggests that fish oil supplementation may have an antiinflammatory effect. | lld:pubmed |
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| pubmed-article:3663263 | pubmed:language | eng | lld:pubmed |
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| pubmed-article:3663263 | pubmed:citationSubset | AIM | lld:pubmed |
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| pubmed-article:3663263 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:3663263 | pubmed:month | Sep | lld:pubmed |
| pubmed-article:3663263 | pubmed:issn | 0004-3591 | lld:pubmed |
| pubmed-article:3663263 | pubmed:author | pubmed-author:CoblynJ SJS | lld:pubmed |
| pubmed-article:3663263 | pubmed:author | pubmed-author:RobinsonD RDR | lld:pubmed |
| pubmed-article:3663263 | pubmed:author | pubmed-author:HouseFF | lld:pubmed |
| pubmed-article:3663263 | pubmed:author | pubmed-author:FraserP APA | lld:pubmed |
| pubmed-article:3663263 | pubmed:author | pubmed-author:HooverR LRL | lld:pubmed |
| pubmed-article:3663263 | pubmed:author | pubmed-author:SperlingR IRI | lld:pubmed |
| pubmed-article:3663263 | pubmed:author | pubmed-author:RUSEJ LJL | lld:pubmed |
| pubmed-article:3663263 | pubmed:author | pubmed-author:WeinblattMM | lld:pubmed |
| pubmed-article:3663263 | pubmed:author | pubmed-author:RobinJ LJL | lld:pubmed |
| pubmed-article:3663263 | pubmed:author | pubmed-author:RavaleseJJ3rd | lld:pubmed |
| pubmed-article:3663263 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:3663263 | pubmed:volume | 30 | lld:pubmed |
| pubmed-article:3663263 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:3663263 | pubmed:authorsComplete | N | lld:pubmed |
| pubmed-article:3663263 | pubmed:pagination | 988-97 | lld:pubmed |
| pubmed-article:3663263 | pubmed:dateRevised | 2007-11-14 | lld:pubmed |
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| pubmed-article:3663263 | pubmed:year | 1987 | lld:pubmed |
| pubmed-article:3663263 | pubmed:articleTitle | Effects of dietary supplementation with marine fish oil on leukocyte lipid mediator generation and function in rheumatoid arthritis. | lld:pubmed |
| pubmed-article:3663263 | pubmed:affiliation | Department of Medicine, Harvard Medical School, Boston, Massachusetts. | lld:pubmed |
| pubmed-article:3663263 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:3663263 | pubmed:publicationType | Research Support, U.S. Gov't, P.H.S. | lld:pubmed |
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