pubmed-article:3580305 | rdf:type | pubmed:Citation | lld:pubmed |
pubmed-article:3580305 | lifeskim:mentions | umls-concept:C0003864 | lld:lifeskim |
pubmed-article:3580305 | lifeskim:mentions | umls-concept:C0003873 | lld:lifeskim |
pubmed-article:3580305 | lifeskim:mentions | umls-concept:C0087111 | lld:lifeskim |
pubmed-article:3580305 | lifeskim:mentions | umls-concept:C0439849 | lld:lifeskim |
pubmed-article:3580305 | lifeskim:mentions | umls-concept:C0014822 | lld:lifeskim |
pubmed-article:3580305 | lifeskim:mentions | umls-concept:C0229671 | lld:lifeskim |
pubmed-article:3580305 | lifeskim:mentions | umls-concept:C0003209 | lld:lifeskim |
pubmed-article:3580305 | lifeskim:mentions | umls-concept:C1280500 | lld:lifeskim |
pubmed-article:3580305 | lifeskim:mentions | umls-concept:C0333348 | lld:lifeskim |
pubmed-article:3580305 | lifeskim:mentions | umls-concept:C1515999 | lld:lifeskim |
pubmed-article:3580305 | pubmed:issue | 4 | lld:pubmed |
pubmed-article:3580305 | pubmed:dateCreated | 1987-7-16 | lld:pubmed |
pubmed-article:3580305 | pubmed:abstractText | Serum erythropoietin (s-Epo) was measured with a sensitive radioimmunoassay method in 58 patients with classical rheumatoid arthritis (n = 41) or seronegative spondyloarthropathies (n = 17). Epo was significantly (P less than 0.001) increased and on an average two times higher than in a healthy population. A correlation was found between Hb and s-Epo (r = -0.46, P less than 0.005), indicating that these patients respond to anaemia with an increase in s-Epo. In order to investigate if inflammation has a direct influence on s-Epo levels a short period of corticosteroid treatment was given to rapidly decrease inflammatory activity. No increase in s-Epo was seen after 1 week. Furthermore, there was a correlation between s-Epo and ESR in all patients (r = 0.59, P less than 0.01). These results indicate that s-Epo is directed by the Hb level, which in turn is influenced by the inflammatory activity: a higher inflammatory activity gives a lower Hb and an increase in s-Epo. In comparison to previously published figures for the relation between Hb and s-Epo these patients seem to have an ordinary Epo response. We conclude that the anaemia of patients with chronic inflammatory joint disease is not caused by a diminished Epo production. | lld:pubmed |
pubmed-article:3580305 | pubmed:language | eng | lld:pubmed |
pubmed-article:3580305 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:3580305 | pubmed:citationSubset | IM | lld:pubmed |
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pubmed-article:3580305 | pubmed:status | MEDLINE | lld:pubmed |
pubmed-article:3580305 | pubmed:month | Apr | lld:pubmed |
pubmed-article:3580305 | pubmed:issn | 0007-1048 | lld:pubmed |
pubmed-article:3580305 | pubmed:author | pubmed-author:HällgrenRR | lld:pubmed |
pubmed-article:3580305 | pubmed:author | pubmed-author:BirgegårdGG | lld:pubmed |
pubmed-article:3580305 | pubmed:author | pubmed-author:CaroJJ | lld:pubmed |
pubmed-article:3580305 | pubmed:issnType | Print | lld:pubmed |
pubmed-article:3580305 | pubmed:volume | 65 | lld:pubmed |
pubmed-article:3580305 | pubmed:owner | NLM | lld:pubmed |
pubmed-article:3580305 | pubmed:authorsComplete | Y | lld:pubmed |
pubmed-article:3580305 | pubmed:pagination | 479-83 | lld:pubmed |
pubmed-article:3580305 | pubmed:dateRevised | 2004-11-17 | lld:pubmed |
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pubmed-article:3580305 | pubmed:year | 1987 | lld:pubmed |
pubmed-article:3580305 | pubmed:articleTitle | Serum erythropoietin in rheumatoid arthritis and other inflammatory arthritides: relationship to anaemia and the effect of anti-inflammatory treatment. | lld:pubmed |
pubmed-article:3580305 | pubmed:publicationType | Journal Article | lld:pubmed |
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