| pubmed-article:3557108 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:3557108 | lifeskim:mentions | umls-concept:C0008633 | lld:lifeskim |
| pubmed-article:3557108 | lifeskim:mentions | umls-concept:C1512977 | lld:lifeskim |
| pubmed-article:3557108 | lifeskim:mentions | umls-concept:C0332597 | lld:lifeskim |
| pubmed-article:3557108 | lifeskim:mentions | umls-concept:C0162326 | lld:lifeskim |
| pubmed-article:3557108 | lifeskim:mentions | umls-concept:C0017259 | lld:lifeskim |
| pubmed-article:3557108 | lifeskim:mentions | umls-concept:C1334043 | lld:lifeskim |
| pubmed-article:3557108 | lifeskim:mentions | umls-concept:C1514873 | lld:lifeskim |
| pubmed-article:3557108 | lifeskim:mentions | umls-concept:C2697616 | lld:lifeskim |
| pubmed-article:3557108 | pubmed:issue | 1 | lld:pubmed |
| pubmed-article:3557108 | pubmed:dateCreated | 1987-4-30 | lld:pubmed |
| pubmed-article:3557108 | pubmed:abstractText | We report experiments designed to test homology dependence for gene conversion between duplicated chromosomal sequences in cultured mammalian cells. The experimental system is such that gene conversion events not associated with reciprocal exchange are recoverable. For this study four plasmids were constructed. Each contains a different duplication of the herpes simplex virus thymidine kinase (HSV tk) gene sequence. In particular, the interacting sequences share different lengths of homology. Our results indicate that for shared homologies between 295 base pairs (bp) and 1.8 kilobase pairs (kbp) in length, conversion is efficient with the rate being directly proportional to the extent of homology. In contrast, conversion with either 200 bp or 95 bp of homology is inefficient, and the rate is reduced at least seven- or 100-fold, respectively, relative to that observed with 295 bp of homology. These results are consistent with the notion that greater than 200 bp of homology are required for efficient gene conversion between repeated chromosomal sequences in mammalian cells. | lld:pubmed |
| pubmed-article:3557108 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:3557108 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:3557108 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:3557108 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:3557108 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:3557108 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:3557108 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:3557108 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:3557108 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:3557108 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:3557108 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:3557108 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:3557108 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:3557108 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:3557108 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:3557108 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:3557108 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:3557108 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:3557108 | pubmed:language | eng | lld:pubmed |
| pubmed-article:3557108 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:3557108 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:3557108 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:3557108 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:3557108 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:3557108 | pubmed:month | Jan | lld:pubmed |
| pubmed-article:3557108 | pubmed:issn | 0016-6731 | lld:pubmed |
| pubmed-article:3557108 | pubmed:author | pubmed-author:LiskayR MRM | lld:pubmed |
| pubmed-article:3557108 | pubmed:author | pubmed-author:LetsouAA | lld:pubmed |
| pubmed-article:3557108 | pubmed:author | pubmed-author:StachelekJ... | lld:pubmed |
| pubmed-article:3557108 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:3557108 | pubmed:volume | 115 | lld:pubmed |
| pubmed-article:3557108 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:3557108 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:3557108 | pubmed:pagination | 161-7 | lld:pubmed |
| pubmed-article:3557108 | pubmed:dateRevised | 2009-11-18 | lld:pubmed |
| pubmed-article:3557108 | pubmed:meshHeading | pubmed-meshheading:3557108-... | lld:pubmed |
| pubmed-article:3557108 | pubmed:meshHeading | pubmed-meshheading:3557108-... | lld:pubmed |
| pubmed-article:3557108 | pubmed:meshHeading | pubmed-meshheading:3557108-... | lld:pubmed |
| pubmed-article:3557108 | pubmed:meshHeading | pubmed-meshheading:3557108-... | lld:pubmed |
| pubmed-article:3557108 | pubmed:meshHeading | pubmed-meshheading:3557108-... | lld:pubmed |
| pubmed-article:3557108 | pubmed:meshHeading | pubmed-meshheading:3557108-... | lld:pubmed |
| pubmed-article:3557108 | pubmed:meshHeading | pubmed-meshheading:3557108-... | lld:pubmed |
| pubmed-article:3557108 | pubmed:meshHeading | pubmed-meshheading:3557108-... | lld:pubmed |
| pubmed-article:3557108 | pubmed:meshHeading | pubmed-meshheading:3557108-... | lld:pubmed |
| pubmed-article:3557108 | pubmed:meshHeading | pubmed-meshheading:3557108-... | lld:pubmed |
| pubmed-article:3557108 | pubmed:year | 1987 | lld:pubmed |
| pubmed-article:3557108 | pubmed:articleTitle | Homology requirement for efficient gene conversion between duplicated chromosomal sequences in mammalian cells. | lld:pubmed |
| pubmed-article:3557108 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:3557108 | pubmed:publicationType | Research Support, U.S. Gov't, P.H.S. | lld:pubmed |
| pubmed-article:3557108 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:3557108 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:3557108 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:3557108 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:3557108 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:3557108 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:3557108 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:3557108 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:3557108 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:3557108 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:3557108 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:3557108 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:3557108 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:3557108 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:3557108 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:3557108 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:3557108 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:3557108 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:3557108 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:3557108 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:3557108 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:3557108 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:3557108 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:3557108 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:3557108 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:3557108 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:3557108 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:3557108 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:3557108 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:3557108 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:3557108 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:3557108 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:3557108 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:3557108 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:3557108 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:3557108 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:3557108 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:3557108 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:3557108 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:3557108 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:3557108 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:3557108 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:3557108 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:3557108 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:3557108 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:3557108 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:3557108 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:3557108 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:3557108 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:3557108 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:3557108 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:3557108 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:3557108 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:3557108 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:3557108 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:3557108 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:3557108 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:3557108 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:3557108 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:3557108 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:3557108 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:3557108 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:3557108 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:3557108 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:3557108 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:3557108 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:3557108 | lld:pubmed |
