Statements in which the resource exists.
SubjectPredicateObjectContext
pubmed-article:3539851rdf:typepubmed:Citationlld:pubmed
pubmed-article:3539851lifeskim:mentionsumls-concept:C0003232lld:lifeskim
pubmed-article:3539851lifeskim:mentionsumls-concept:C0030705lld:lifeskim
pubmed-article:3539851lifeskim:mentionsumls-concept:C0205721lld:lifeskim
pubmed-article:3539851lifeskim:mentionsumls-concept:C0034656lld:lifeskim
pubmed-article:3539851lifeskim:mentionsumls-concept:C0005841lld:lifeskim
pubmed-article:3539851lifeskim:mentionsumls-concept:C0018183lld:lifeskim
pubmed-article:3539851lifeskim:mentionsumls-concept:C0376152lld:lifeskim
pubmed-article:3539851lifeskim:mentionsumls-concept:C0332835lld:lifeskim
pubmed-article:3539851lifeskim:mentionsumls-concept:C1707455lld:lifeskim
pubmed-article:3539851lifeskim:mentionsumls-concept:C1879316lld:lifeskim
pubmed-article:3539851lifeskim:mentionsumls-concept:C1708528lld:lifeskim
pubmed-article:3539851lifeskim:mentionsumls-concept:C0023981lld:lifeskim
pubmed-article:3539851lifeskim:mentionsumls-concept:C0205373lld:lifeskim
pubmed-article:3539851pubmed:issue12lld:pubmed
pubmed-article:3539851pubmed:dateCreated1987-2-19lld:pubmed
pubmed-article:3539851pubmed:abstractTextOne hundred twelve patients with hematologic malignancies underwent marrow transplantation from HLA-matched sibling donors and were randomized to receive either prophylactic granulocyte transfusions (PG, 67 patients) or prophylactic systemic antibiotics (PSA, 45 patients) as prophylaxis against nosocomial infections. Patients were treated in conventional hospital rooms and studied until day 100 post-transplant. For the entire study period, 26 patients (39%) in the PG group developed septicemia compared to 15 patients (33%) in the PSA group. Twenty-eight patients (42%) in the PG group developed local major infections compared to 19 patients (42%) in the PSA group. Ten patients (15%) in the PG group developed viral interstitial pneumonitis compared to 6 patients (13%) in the PSA group. None of these differences were statistically significant. There was no difference in the incidence of bacterial or fungal infections or viral interstitial pneumonitis between the two groups during the granulocytopenic or post-engraftment period. There was no difference in the incidence and severity of graft-versus-host-disease (GVHD). Inability to carry out the prophylaxis was frequent in the PG group, with complications necessitating discontinuance of transfusion in 24% of the recipients and 13% of the donors. The use of PG as an infection prophylaxis modality in marrow transplantation is not supported by this study, as it is difficult to carry out and because PG did not show any advantage over the use of PSA in preventing nosocomial infections.lld:pubmed
pubmed-article:3539851pubmed:granthttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:3539851pubmed:granthttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:3539851pubmed:granthttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:3539851pubmed:languageenglld:pubmed
pubmed-article:3539851pubmed:journalhttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:3539851pubmed:citationSubsetIMlld:pubmed
pubmed-article:3539851pubmed:chemicalhttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:3539851pubmed:statusMEDLINElld:pubmed
pubmed-article:3539851pubmed:monthDeclld:pubmed
pubmed-article:3539851pubmed:issn0195-9417lld:pubmed
pubmed-article:3539851pubmed:authorpubmed-author:ThomasE DEDlld:pubmed
pubmed-article:3539851pubmed:authorpubmed-author:BucknerC DCDlld:pubmed
pubmed-article:3539851pubmed:authorpubmed-author:CliftR ARAlld:pubmed
pubmed-article:3539851pubmed:authorpubmed-author:NelsonNNlld:pubmed
pubmed-article:3539851pubmed:authorpubmed-author:CountsG WGWlld:pubmed
pubmed-article:3539851pubmed:authorpubmed-author:MeyersJ DJDlld:pubmed
pubmed-article:3539851pubmed:authorpubmed-author:PetersenF BFBlld:pubmed
pubmed-article:3539851pubmed:issnTypePrintlld:pubmed
pubmed-article:3539851pubmed:volume7lld:pubmed
pubmed-article:3539851pubmed:ownerNLMlld:pubmed
pubmed-article:3539851pubmed:authorsCompleteYlld:pubmed
pubmed-article:3539851pubmed:pagination586-92lld:pubmed
pubmed-article:3539851pubmed:dateRevised2007-11-14lld:pubmed
pubmed-article:3539851pubmed:meshHeadingpubmed-meshheading:3539851-...lld:pubmed
pubmed-article:3539851pubmed:meshHeadingpubmed-meshheading:3539851-...lld:pubmed
pubmed-article:3539851pubmed:meshHeadingpubmed-meshheading:3539851-...lld:pubmed
pubmed-article:3539851pubmed:meshHeadingpubmed-meshheading:3539851-...lld:pubmed
pubmed-article:3539851pubmed:meshHeadingpubmed-meshheading:3539851-...lld:pubmed
pubmed-article:3539851pubmed:meshHeadingpubmed-meshheading:3539851-...lld:pubmed
pubmed-article:3539851pubmed:meshHeadingpubmed-meshheading:3539851-...lld:pubmed
pubmed-article:3539851pubmed:meshHeadingpubmed-meshheading:3539851-...lld:pubmed
pubmed-article:3539851pubmed:meshHeadingpubmed-meshheading:3539851-...lld:pubmed
pubmed-article:3539851pubmed:meshHeadingpubmed-meshheading:3539851-...lld:pubmed
pubmed-article:3539851pubmed:meshHeadingpubmed-meshheading:3539851-...lld:pubmed
pubmed-article:3539851pubmed:meshHeadingpubmed-meshheading:3539851-...lld:pubmed
pubmed-article:3539851pubmed:meshHeadingpubmed-meshheading:3539851-...lld:pubmed
pubmed-article:3539851pubmed:meshHeadingpubmed-meshheading:3539851-...lld:pubmed
pubmed-article:3539851pubmed:meshHeadingpubmed-meshheading:3539851-...lld:pubmed
pubmed-article:3539851pubmed:year1986lld:pubmed
pubmed-article:3539851pubmed:articleTitlePrevention of nosocomial infections in marrow transplant patients: a prospective randomized comparison of systemic antibiotics versus granulocyte transfusions.lld:pubmed
pubmed-article:3539851pubmed:publicationTypeJournal Articlelld:pubmed
pubmed-article:3539851pubmed:publicationTypeClinical Triallld:pubmed
pubmed-article:3539851pubmed:publicationTypeComparative Studylld:pubmed
pubmed-article:3539851pubmed:publicationTypeResearch Support, U.S. Gov't, P.H.S.lld:pubmed
pubmed-article:3539851pubmed:publicationTypeRandomized Controlled Triallld:pubmed
pubmed-article:3539851pubmed:publicationTypeResearch Support, Non-U.S. Gov'tlld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:3539851lld:pubmed