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pubmed-article:3498498pubmed:abstractTextIn a defined medium in which transferrin (3 micrograms/ml) was the only source of exogenous proteins, Raji cells of the human pre-B lymphoblastoid cell line died within 48 h after forming polykaryons. The simple addition of purified C3 at a concentration equal to or higher than 3 micrograms/ml allowed Raji cells to divide. This preliminary report provides a defined system for studying the mitogenic effect of human C3 or C3 fragments upon proliferation of human B-cells lines.lld:pubmed
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pubmed-article:3498498pubmed:articleTitle[C3 stimulates the proliferation of human pre-B Raji cells].lld:pubmed
pubmed-article:3498498pubmed:affiliationUA 041163, ICIG, Hôpital Paul-Brousse, Villejuif, France.lld:pubmed
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