pubmed-article:3491291 | rdf:type | pubmed:Citation | lld:pubmed |
pubmed-article:3491291 | lifeskim:mentions | umls-concept:C0439849 | lld:lifeskim |
pubmed-article:3491291 | lifeskim:mentions | umls-concept:C0029016 | lld:lifeskim |
pubmed-article:3491291 | lifeskim:mentions | umls-concept:C0445223 | lld:lifeskim |
pubmed-article:3491291 | lifeskim:mentions | umls-concept:C1552599 | lld:lifeskim |
pubmed-article:3491291 | lifeskim:mentions | umls-concept:C1880022 | lld:lifeskim |
pubmed-article:3491291 | lifeskim:mentions | umls-concept:C1704787 | lld:lifeskim |
pubmed-article:3491291 | lifeskim:mentions | umls-concept:C0591833 | lld:lifeskim |
pubmed-article:3491291 | pubmed:issue | 7 | lld:pubmed |
pubmed-article:3491291 | pubmed:dateCreated | 1987-1-20 | lld:pubmed |
pubmed-article:3491291 | pubmed:databankReference | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:3491291 | pubmed:abstractText | A 1.6-kilobase cDNA (A-raf) has been isolated from a murine spleen cDNA library which encodes part of a protein related to the raf oncogene. Its amino acid sequence has 85% homology to raf in a central portion of 100 amino acids. In contrast to raf, A-raf shows a highly restricted tissue distribution of expression, with highest levels observed in epididymis, followed by intestine. When incorporated into a retrovirus, the resulting gag-A-raf fusion gene causes transformation in vitro and induces tumors in newborn mice. Thus, A-raf represents a new proto-oncogene. Transformation by A-raf is independent of ras gene function, as is the case for raf and mos but not other oncogenes. | lld:pubmed |
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pubmed-article:3491291 | pubmed:language | eng | lld:pubmed |
pubmed-article:3491291 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:3491291 | pubmed:citationSubset | IM | lld:pubmed |
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pubmed-article:3491291 | pubmed:status | MEDLINE | lld:pubmed |
pubmed-article:3491291 | pubmed:month | Jul | lld:pubmed |
pubmed-article:3491291 | pubmed:issn | 0270-7306 | lld:pubmed |
pubmed-article:3491291 | pubmed:author | pubmed-author:RappU RUR | lld:pubmed |
pubmed-article:3491291 | pubmed:author | pubmed-author:GunnellMM | lld:pubmed |
pubmed-article:3491291 | pubmed:author | pubmed-author:ClevelandJJ | lld:pubmed |
pubmed-article:3491291 | pubmed:author | pubmed-author:BonnetRR | lld:pubmed |
pubmed-article:3491291 | pubmed:author | pubmed-author:HuleihelMM | lld:pubmed |
pubmed-article:3491291 | pubmed:author | pubmed-author:GoldsboroughM... | lld:pubmed |
pubmed-article:3491291 | pubmed:issnType | Print | lld:pubmed |
pubmed-article:3491291 | pubmed:volume | 6 | lld:pubmed |
pubmed-article:3491291 | pubmed:owner | NLM | lld:pubmed |
pubmed-article:3491291 | pubmed:authorsComplete | Y | lld:pubmed |
pubmed-article:3491291 | pubmed:pagination | 2655-62 | lld:pubmed |
pubmed-article:3491291 | pubmed:dateRevised | 2009-11-18 | lld:pubmed |
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pubmed-article:3491291 | pubmed:year | 1986 | lld:pubmed |
pubmed-article:3491291 | pubmed:articleTitle | Characterization of murine A-raf, a new oncogene related to the v-raf oncogene. | lld:pubmed |
pubmed-article:3491291 | pubmed:publicationType | Journal Article | lld:pubmed |
pubmed-article:3491291 | pubmed:publicationType | Research Support, U.S. Gov't, P.H.S. | lld:pubmed |
entrez-gene:11836 | entrezgene:pubmed | pubmed-article:3491291 | lld:entrezgene |
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