| pubmed-article:3484799 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:3484799 | lifeskim:mentions | umls-concept:C0034693 | lld:lifeskim |
| pubmed-article:3484799 | lifeskim:mentions | umls-concept:C0034786 | lld:lifeskim |
| pubmed-article:3484799 | lifeskim:mentions | umls-concept:C0043481 | lld:lifeskim |
| pubmed-article:3484799 | lifeskim:mentions | umls-concept:C0011155 | lld:lifeskim |
| pubmed-article:3484799 | lifeskim:mentions | umls-concept:C2700158 | lld:lifeskim |
| pubmed-article:3484799 | pubmed:issue | 4 | lld:pubmed |
| pubmed-article:3484799 | pubmed:dateCreated | 1986-2-26 | lld:pubmed |
| pubmed-article:3484799 | pubmed:abstractText | Androgen binding has been studied in the prostate cytosol of zinc deficient rats by charcoal assays. Rats were housed individually in plastic cages and maintained on a zinc deficient diet for 3 months. The cytosol fraction of prostate gland was incubated with various concentrations of tritiated methyltrienolone (3H-R1881, a synthetic androgen) alone or in the presence of 500-fold excess of radioinert R1881. Scatchard analysis of the data revealed that the number of androgen binding sites in the cytosol fraction of the zinc deficient rat prostate was 31 +/- 5.2 fmol/mg cytosol protein. This was significantly lower than that (84 +/- 11.5 fmol/mg protein) of the controls. Their dissociation constant (Kd = 1.6 +/- 0.6 nM) on the other hand was not different from that (1.7 +/- 0.7 nM) of control animals. This decrease in the concentration of cytosol receptor sites in the zinc deficient state suggests that this metal is involved in the androgen-binding process in the target cells. | lld:pubmed |
| pubmed-article:3484799 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:3484799 | pubmed:language | eng | lld:pubmed |
| pubmed-article:3484799 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:3484799 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:3484799 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:3484799 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:3484799 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:3484799 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:3484799 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:3484799 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:3484799 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:3484799 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:3484799 | pubmed:month | Jan | lld:pubmed |
| pubmed-article:3484799 | pubmed:issn | 0024-3205 | lld:pubmed |
| pubmed-article:3484799 | pubmed:author | pubmed-author:RennertO MOM | lld:pubmed |
| pubmed-article:3484799 | pubmed:author | pubmed-author:ChanW YWY | lld:pubmed |
| pubmed-article:3484799 | pubmed:author | pubmed-author:ChungK WKW | lld:pubmed |
| pubmed-article:3484799 | pubmed:author | pubmed-author:KimS YSY | lld:pubmed |
| pubmed-article:3484799 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:3484799 | pubmed:day | 27 | lld:pubmed |
| pubmed-article:3484799 | pubmed:volume | 38 | lld:pubmed |
| pubmed-article:3484799 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:3484799 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:3484799 | pubmed:pagination | 351-6 | lld:pubmed |
| pubmed-article:3484799 | pubmed:dateRevised | 2007-11-14 | lld:pubmed |
| pubmed-article:3484799 | pubmed:meshHeading | pubmed-meshheading:3484799-... | lld:pubmed |
| pubmed-article:3484799 | pubmed:meshHeading | pubmed-meshheading:3484799-... | lld:pubmed |
| pubmed-article:3484799 | pubmed:meshHeading | pubmed-meshheading:3484799-... | lld:pubmed |
| pubmed-article:3484799 | pubmed:meshHeading | pubmed-meshheading:3484799-... | lld:pubmed |
| pubmed-article:3484799 | pubmed:meshHeading | pubmed-meshheading:3484799-... | lld:pubmed |
| pubmed-article:3484799 | pubmed:meshHeading | pubmed-meshheading:3484799-... | lld:pubmed |
| pubmed-article:3484799 | pubmed:meshHeading | pubmed-meshheading:3484799-... | lld:pubmed |
| pubmed-article:3484799 | pubmed:meshHeading | pubmed-meshheading:3484799-... | lld:pubmed |
| pubmed-article:3484799 | pubmed:meshHeading | pubmed-meshheading:3484799-... | lld:pubmed |
| pubmed-article:3484799 | pubmed:meshHeading | pubmed-meshheading:3484799-... | lld:pubmed |
| pubmed-article:3484799 | pubmed:meshHeading | pubmed-meshheading:3484799-... | lld:pubmed |
| pubmed-article:3484799 | pubmed:meshHeading | pubmed-meshheading:3484799-... | lld:pubmed |
| pubmed-article:3484799 | pubmed:meshHeading | pubmed-meshheading:3484799-... | lld:pubmed |
| pubmed-article:3484799 | pubmed:year | 1986 | lld:pubmed |
| pubmed-article:3484799 | pubmed:articleTitle | Androgen receptors in ventral prostate glands of zinc deficient rats. | lld:pubmed |
| pubmed-article:3484799 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:3484799 | pubmed:publicationType | Research Support, U.S. Gov't, P.H.S. | lld:pubmed |
| pubmed-article:3484799 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
