pubmed-article:3479669 | rdf:type | pubmed:Citation | lld:pubmed |
pubmed-article:3479669 | lifeskim:mentions | umls-concept:C0007450 | lld:lifeskim |
pubmed-article:3479669 | lifeskim:mentions | umls-concept:C0003811 | lld:lifeskim |
pubmed-article:3479669 | lifeskim:mentions | umls-concept:C0003195 | lld:lifeskim |
pubmed-article:3479669 | lifeskim:mentions | umls-concept:C0012471 | lld:lifeskim |
pubmed-article:3479669 | lifeskim:mentions | umls-concept:C1280500 | lld:lifeskim |
pubmed-article:3479669 | lifeskim:mentions | umls-concept:C1314939 | lld:lifeskim |
pubmed-article:3479669 | pubmed:issue | 21 | lld:pubmed |
pubmed-article:3479669 | pubmed:dateCreated | 1987-12-29 | lld:pubmed |
pubmed-article:3479669 | pubmed:abstractText | The effects of prostaglandin F2 alpha (PGF2 alpha) on ouabain-induced cardiac arrhythmias were investigated in chloralose-anaesthetized cats. Bilateral vagotomy and atropine intervention were employed to elucidate the involvement of vagal neural influences. PGF2 alpha (2-16 micrograms/kg i.v. bolus) predominantly suppressed the ouabain-induced ventricular and supraventricular arrhythmias and less commonly aggravated them in vagi-intact cats. The antiarrhythmic effect of PGF2 alpha was considerably, but not statistically significantly, decreased while its arrhythmogenic effect was significantly (p less than 0.05) increased in atropine-pretreated group. In vagotomised group PGF2 alpha failed to abolish the arrhythmias but it aggravated them to a degree comparable to that observed in vagi-intact group. It is concluded that the PGF2 alpha exhibits both antiarrhythmic and arrhythmogenic properties and these are largely due to elicitation of two opposing neural reflexes - one being protective and another being deleterious to ouabain-induced arrhythmias. | lld:pubmed |
pubmed-article:3479669 | pubmed:language | eng | lld:pubmed |
pubmed-article:3479669 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:3479669 | pubmed:citationSubset | IM | lld:pubmed |
pubmed-article:3479669 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:3479669 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:3479669 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:3479669 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:3479669 | pubmed:status | MEDLINE | lld:pubmed |
pubmed-article:3479669 | pubmed:month | Nov | lld:pubmed |
pubmed-article:3479669 | pubmed:issn | 0024-3205 | lld:pubmed |
pubmed-article:3479669 | pubmed:author | pubmed-author:RaoT STS | lld:pubmed |
pubmed-article:3479669 | pubmed:author | pubmed-author:SethS DSD | lld:pubmed |
pubmed-article:3479669 | pubmed:author | pubmed-author:ManchandaS... | lld:pubmed |
pubmed-article:3479669 | pubmed:author | pubmed-author:NayakRR | lld:pubmed |
pubmed-article:3479669 | pubmed:issnType | Print | lld:pubmed |
pubmed-article:3479669 | pubmed:day | 23 | lld:pubmed |
pubmed-article:3479669 | pubmed:volume | 41 | lld:pubmed |
pubmed-article:3479669 | pubmed:owner | NLM | lld:pubmed |
pubmed-article:3479669 | pubmed:authorsComplete | Y | lld:pubmed |
pubmed-article:3479669 | pubmed:pagination | 2363-72 | lld:pubmed |
pubmed-article:3479669 | pubmed:dateRevised | 2007-11-15 | lld:pubmed |
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pubmed-article:3479669 | pubmed:year | 1987 | lld:pubmed |
pubmed-article:3479669 | pubmed:articleTitle | The vagal involvement in the antiarrhythmic and arrhythmogenic effects of prostaglandin F2 alpha on ouabain-induced cardiac arrhythmias in cats. | lld:pubmed |
pubmed-article:3479669 | pubmed:affiliation | Department of Pharmacology, All India Institute of Medical Sciences, New Delhi. | lld:pubmed |
pubmed-article:3479669 | pubmed:publicationType | Journal Article | lld:pubmed |
pubmed-article:3479669 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |