| pubmed-article:3478099 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:3478099 | lifeskim:mentions | umls-concept:C0005699 | lld:lifeskim |
| pubmed-article:3478099 | lifeskim:mentions | umls-concept:C0023473 | lld:lifeskim |
| pubmed-article:3478099 | lifeskim:mentions | umls-concept:C0008633 | lld:lifeskim |
| pubmed-article:3478099 | lifeskim:mentions | umls-concept:C0040715 | lld:lifeskim |
| pubmed-article:3478099 | lifeskim:mentions | umls-concept:C1522702 | lld:lifeskim |
| pubmed-article:3478099 | lifeskim:mentions | umls-concept:C0004083 | lld:lifeskim |
| pubmed-article:3478099 | lifeskim:mentions | umls-concept:C0599718 | lld:lifeskim |
| pubmed-article:3478099 | lifeskim:mentions | umls-concept:C0599813 | lld:lifeskim |
| pubmed-article:3478099 | lifeskim:mentions | umls-concept:C0599893 | lld:lifeskim |
| pubmed-article:3478099 | pubmed:issue | 5 | lld:pubmed |
| pubmed-article:3478099 | pubmed:dateCreated | 1987-12-11 | lld:pubmed |
| pubmed-article:3478099 | pubmed:abstractText | An identical reciprocal translocation between the long arms of chromosomes 3 and 21 with breakpoints in bands 3q26 and 21q22, t(3;21)(q26;q22), was found in three male patients with the blast phase of chronic myelogenous leukemia (CML). The abnormality was clonal in all three patients and was always accompanied by either a standard or variant 9;22 translocation resulting in a Philadelphia chromosome (Ph1). In two cases, the t(3;21) was the only abnormality other than a t(9;22) in the primary clone. Serial studies of one patient demonstrated that the t(3;21) occurred as a result of clonal evolution near the time of development of the blast phase. We have not observed the t(3;21) in greater than 500 patients with CML in the chronic phase. Thus, the t(3;21) is a new recurring cytogenetic abnormality associated with the blast phase of CML. | lld:pubmed |
| pubmed-article:3478099 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:3478099 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:3478099 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:3478099 | pubmed:language | eng | lld:pubmed |
| pubmed-article:3478099 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:3478099 | pubmed:citationSubset | AIM | lld:pubmed |
| pubmed-article:3478099 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:3478099 | pubmed:month | Nov | lld:pubmed |
| pubmed-article:3478099 | pubmed:issn | 0006-4971 | lld:pubmed |
| pubmed-article:3478099 | pubmed:author | pubmed-author:RowleyJ DJD | lld:pubmed |
| pubmed-article:3478099 | pubmed:author | pubmed-author:LarsonR ARA | lld:pubmed |
| pubmed-article:3478099 | pubmed:author | pubmed-author:DiazM OMO | lld:pubmed |
| pubmed-article:3478099 | pubmed:author | pubmed-author:RubinC MCM | lld:pubmed |
| pubmed-article:3478099 | pubmed:author | pubmed-author:Le BeauM MMM | lld:pubmed |
| pubmed-article:3478099 | pubmed:author | pubmed-author:BitterM AMA | lld:pubmed |
| pubmed-article:3478099 | pubmed:author | pubmed-author:CarrinoJ JJJ | lld:pubmed |
| pubmed-article:3478099 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:3478099 | pubmed:volume | 70 | lld:pubmed |
| pubmed-article:3478099 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:3478099 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:3478099 | pubmed:pagination | 1338-42 | lld:pubmed |
| pubmed-article:3478099 | pubmed:dateRevised | 2007-11-14 | lld:pubmed |
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| pubmed-article:3478099 | pubmed:meshHeading | pubmed-meshheading:3478099-... | lld:pubmed |
| pubmed-article:3478099 | pubmed:year | 1987 | lld:pubmed |
| pubmed-article:3478099 | pubmed:articleTitle | Association of a chromosomal 3;21 translocation with the blast phase of chronic myelogenous leukemia. | lld:pubmed |
| pubmed-article:3478099 | pubmed:affiliation | Department of Medicine, University of Chicago, IL. | lld:pubmed |
| pubmed-article:3478099 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:3478099 | pubmed:publicationType | Research Support, U.S. Gov't, P.H.S. | lld:pubmed |
| pubmed-article:3478099 | pubmed:publicationType | Research Support, U.S. Gov't, Non-P.H.S. | lld:pubmed |
| pubmed-article:3478099 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
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