| pubmed-article:3427906 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:3427906 | lifeskim:mentions | umls-concept:C0018398 | lld:lifeskim |
| pubmed-article:3427906 | lifeskim:mentions | umls-concept:C0014442 | lld:lifeskim |
| pubmed-article:3427906 | lifeskim:mentions | umls-concept:C0023884 | lld:lifeskim |
| pubmed-article:3427906 | lifeskim:mentions | umls-concept:C0015109 | lld:lifeskim |
| pubmed-article:3427906 | lifeskim:mentions | umls-concept:C0039593 | lld:lifeskim |
| pubmed-article:3427906 | lifeskim:mentions | umls-concept:C0022885 | lld:lifeskim |
| pubmed-article:3427906 | lifeskim:mentions | umls-concept:C0441655 | lld:lifeskim |
| pubmed-article:3427906 | pubmed:issue | 2 | lld:pubmed |
| pubmed-article:3427906 | pubmed:dateCreated | 1988-3-2 | lld:pubmed |
| pubmed-article:3427906 | pubmed:abstractText | The oxidative demethylation of the model substrate ethylmorphine has been characterized for the first time in the liver of a fish (Poecilia reticulata). The enzyme showed maximal activity at 35 degrees C and pH values higher than 8. The values of Km and Vmax for the reaction were 0.83 +/- 0.11 mM and 4.64 +/- 0.81 nmol HCHO/(mg microsomal protein) per min. The activity is attributed to the cytochrome P-450-dependent monoxygenase system, since it is inhibited by CO and requires NADPH; moreover it is inhibited competitively by alpha-naphthoflavone and non-competitively by metyrapone. The enzyme activity is induced by a two-week treatment of fish with phenobarbital and may be associated with a protein band of Mr 54,000. | lld:pubmed |
| pubmed-article:3427906 | pubmed:language | eng | lld:pubmed |
| pubmed-article:3427906 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:3427906 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:3427906 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:3427906 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:3427906 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:3427906 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:3427906 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:3427906 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:3427906 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:3427906 | pubmed:issn | 0305-0491 | lld:pubmed |
| pubmed-article:3427906 | pubmed:author | pubmed-author:De AngelisGG | lld:pubmed |
| pubmed-article:3427906 | pubmed:author | pubmed-author:FunariEE | lld:pubmed |
| pubmed-article:3427906 | pubmed:author | pubmed-author:VittozziLL | lld:pubmed |
| pubmed-article:3427906 | pubmed:author | pubmed-author:TestaiEE | lld:pubmed |
| pubmed-article:3427906 | pubmed:author | pubmed-author:VerdinaAA | lld:pubmed |
| pubmed-article:3427906 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:3427906 | pubmed:volume | 88 | lld:pubmed |
| pubmed-article:3427906 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:3427906 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:3427906 | pubmed:pagination | 619-24 | lld:pubmed |
| pubmed-article:3427906 | pubmed:dateRevised | 2006-11-15 | lld:pubmed |
| pubmed-article:3427906 | pubmed:meshHeading | pubmed-meshheading:3427906-... | lld:pubmed |
| pubmed-article:3427906 | pubmed:meshHeading | pubmed-meshheading:3427906-... | lld:pubmed |
| pubmed-article:3427906 | pubmed:meshHeading | pubmed-meshheading:3427906-... | lld:pubmed |
| pubmed-article:3427906 | pubmed:meshHeading | pubmed-meshheading:3427906-... | lld:pubmed |
| pubmed-article:3427906 | pubmed:meshHeading | pubmed-meshheading:3427906-... | lld:pubmed |
| pubmed-article:3427906 | pubmed:meshHeading | pubmed-meshheading:3427906-... | lld:pubmed |
| pubmed-article:3427906 | pubmed:meshHeading | pubmed-meshheading:3427906-... | lld:pubmed |
| pubmed-article:3427906 | pubmed:meshHeading | pubmed-meshheading:3427906-... | lld:pubmed |
| pubmed-article:3427906 | pubmed:meshHeading | pubmed-meshheading:3427906-... | lld:pubmed |
| pubmed-article:3427906 | pubmed:meshHeading | pubmed-meshheading:3427906-... | lld:pubmed |
| pubmed-article:3427906 | pubmed:meshHeading | pubmed-meshheading:3427906-... | lld:pubmed |
| pubmed-article:3427906 | pubmed:meshHeading | pubmed-meshheading:3427906-... | lld:pubmed |
| pubmed-article:3427906 | pubmed:year | 1987 | lld:pubmed |
| pubmed-article:3427906 | pubmed:articleTitle | Xenobiotic-metabolizing enzyme systems in test fish--II. The ethylmorphine N-demethylase activity of guppy (Poecilia reticulata) liver. | lld:pubmed |
| pubmed-article:3427906 | pubmed:affiliation | Istituto Superiore di Sanità, Department of Comparative Toxicology and Ecotoxicology, Roma, Italy. | lld:pubmed |
| pubmed-article:3427906 | pubmed:publicationType | Journal Article | lld:pubmed |
