Statements in which the resource exists.
SubjectPredicateObjectContext
pubmed-article:342007rdf:typepubmed:Citationlld:pubmed
pubmed-article:342007lifeskim:mentionsumls-concept:C0023494lld:lifeskim
pubmed-article:342007lifeskim:mentionsumls-concept:C0936012lld:lifeskim
pubmed-article:342007pubmed:issue3lld:pubmed
pubmed-article:342007pubmed:dateCreated1978-4-17lld:pubmed
pubmed-article:342007pubmed:abstractTextA 68-yr-old male with chronic lymphocytic leukemia (CLL) presented with splenomegaly and skin infiltration but no lymphadenopathy. The peripheral blood WBC cound was 300 x 10(9)/liter, with 95% small mature-appearing lymphocytes that were E-rosette positive and EAC-rosette negative. Further characterization of the patient's cells was performed using antisera with known lymphoid sub-population specificity. Anti-p23,30, which reacts with normal circulating B cells but not with T cells or thymocytes, was unreactive with the patient's cells. Anti-311, which reacts with both thymocytes and circulating T cells, was reactive with the patient's cells. Anti-Bk, which reacts only with thymocytes and not with circulating T-cells, failed to react with the patient's cells. The enzyme terminal deoxynucleotidyl transferase, present in thymocytes but absent for circulating T-cells, was also absent from the patient's lymphoid cells. Multimarker analysis therefore showed a mature T-lymphocyte phenotype on this patient's leukemia cells. Further functional analysis will probably show that such cells represent clonal expansion of a mature T-cell subpopulation, analogous to the B-cell clonality of common-variant CLL.lld:pubmed
pubmed-article:342007pubmed:languageenglld:pubmed
pubmed-article:342007pubmed:journalhttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:342007pubmed:citationSubsetAIMlld:pubmed
pubmed-article:342007pubmed:chemicalhttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:342007pubmed:chemicalhttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:342007pubmed:statusMEDLINElld:pubmed
pubmed-article:342007pubmed:monthMarlld:pubmed
pubmed-article:342007pubmed:issn0006-4971lld:pubmed
pubmed-article:342007pubmed:authorpubmed-author:SchlossmanS...lld:pubmed
pubmed-article:342007pubmed:authorpubmed-author:MoloneyW CWClld:pubmed
pubmed-article:342007pubmed:authorpubmed-author:RosenthalD...lld:pubmed
pubmed-article:342007pubmed:authorpubmed-author:YanovichSSlld:pubmed
pubmed-article:342007pubmed:authorpubmed-author:MarksS MSMlld:pubmed
pubmed-article:342007pubmed:issnTypePrintlld:pubmed
pubmed-article:342007pubmed:volume51lld:pubmed
pubmed-article:342007pubmed:ownerNLMlld:pubmed
pubmed-article:342007pubmed:authorsCompleteYlld:pubmed
pubmed-article:342007pubmed:pagination435-8lld:pubmed
pubmed-article:342007pubmed:dateRevised2007-11-15lld:pubmed
pubmed-article:342007pubmed:meshHeadingpubmed-meshheading:342007-H...lld:pubmed
pubmed-article:342007pubmed:meshHeadingpubmed-meshheading:342007-A...lld:pubmed
pubmed-article:342007pubmed:meshHeadingpubmed-meshheading:342007-T...lld:pubmed
pubmed-article:342007pubmed:meshHeadingpubmed-meshheading:342007-A...lld:pubmed
pubmed-article:342007pubmed:meshHeadingpubmed-meshheading:342007-M...lld:pubmed
pubmed-article:342007pubmed:meshHeadingpubmed-meshheading:342007-L...lld:pubmed
pubmed-article:342007pubmed:meshHeadingpubmed-meshheading:342007-F...lld:pubmed
pubmed-article:342007pubmed:meshHeadingpubmed-meshheading:342007-P...lld:pubmed
pubmed-article:342007pubmed:meshHeadingpubmed-meshheading:342007-T...lld:pubmed
pubmed-article:342007pubmed:meshHeadingpubmed-meshheading:342007-R...lld:pubmed
pubmed-article:342007pubmed:year1978lld:pubmed
pubmed-article:342007pubmed:articleTitleMultimarker analysis of T-cell chronic lymphocytic leukemia.lld:pubmed
pubmed-article:342007pubmed:publicationTypeJournal Articlelld:pubmed
pubmed-article:342007pubmed:publicationTypeResearch Support, U.S. Gov't, P.H.S.lld:pubmed
pubmed-article:342007pubmed:publicationTypeCase Reportslld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:342007lld:pubmed