| pubmed-article:3416873 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:3416873 | lifeskim:mentions | umls-concept:C1135918 | lld:lifeskim |
| pubmed-article:3416873 | lifeskim:mentions | umls-concept:C0003483 | lld:lifeskim |
| pubmed-article:3416873 | lifeskim:mentions | umls-concept:C0521449 | lld:lifeskim |
| pubmed-article:3416873 | lifeskim:mentions | umls-concept:C0086045 | lld:lifeskim |
| pubmed-article:3416873 | lifeskim:mentions | umls-concept:C1705480 | lld:lifeskim |
| pubmed-article:3416873 | lifeskim:mentions | umls-concept:C0005919 | lld:lifeskim |
| pubmed-article:3416873 | lifeskim:mentions | umls-concept:C1996904 | lld:lifeskim |
| pubmed-article:3416873 | lifeskim:mentions | umls-concept:C1948023 | lld:lifeskim |
| pubmed-article:3416873 | lifeskim:mentions | umls-concept:C0596235 | lld:lifeskim |
| pubmed-article:3416873 | lifeskim:mentions | umls-concept:C0851285 | lld:lifeskim |
| pubmed-article:3416873 | lifeskim:mentions | umls-concept:C1880497 | lld:lifeskim |
| pubmed-article:3416873 | lifeskim:mentions | umls-concept:C0205132 | lld:lifeskim |
| pubmed-article:3416873 | pubmed:issue | 1 | lld:pubmed |
| pubmed-article:3416873 | pubmed:dateCreated | 1988-10-21 | lld:pubmed |
| pubmed-article:3416873 | pubmed:abstractText | The characteristics of intracellular Ca2+ transient induced by vasopressin and bombesin in aortic smooth muscle cells were studied using flow cytometric analysis of indo-1 loaded cells. The two hormones induced a rapid and transient rise in [Ca2+]i. This Ca2+ transient was independent of the presence of extracellular Ca2+. Addition of bombesin to cells that have already been stimulated by vasopressin (or conversely the addition of vasopressin to bombesin-stimulated cells) results in a second Ca2+ transient that has a smaller amplitude. This transient is the same when the external Ca2+ concentration is lowered from 1.8 mM to 50 nM, suggesting that the agonist-sensitive pool reloaded using the Ca2+ that has been previously released into the cytoplasm. Intracellular Ca2+ pools that have been depleted by a prolonged incubation of the cells in a low Ca2+ medium can be refilled by shifting cells to a high Ca2+ medium. The reloading was analyzed in detail and found to be a slow process. It is hardly affected by Ni2+ or by (-)D888, a potent inhibitor of the voltage-dependent Ca2+ channels. It is accelerated when Ca2+ uptake by the Na+/Ca2+ exchange system is stimulated. The results suggest that Ca2+ homeostasis in aortic smooth muscle cells is achieved using mechanisms that are distinct from those operating in various acini and in striated muscles. | lld:pubmed |
| pubmed-article:3416873 | pubmed:language | eng | lld:pubmed |
| pubmed-article:3416873 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:3416873 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:3416873 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:3416873 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:3416873 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:3416873 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:3416873 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:3416873 | pubmed:month | Sep | lld:pubmed |
| pubmed-article:3416873 | pubmed:issn | 0014-2956 | lld:pubmed |
| pubmed-article:3416873 | pubmed:author | pubmed-author:LazdunskiMM | lld:pubmed |
| pubmed-article:3416873 | pubmed:author | pubmed-author:FrelinCC | lld:pubmed |
| pubmed-article:3416873 | pubmed:author | pubmed-author:BreittmayerJ... | lld:pubmed |
| pubmed-article:3416873 | pubmed:author | pubmed-author:VignePP | lld:pubmed |
| pubmed-article:3416873 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:3416873 | pubmed:day | 1 | lld:pubmed |
| pubmed-article:3416873 | pubmed:volume | 176 | lld:pubmed |
| pubmed-article:3416873 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:3416873 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:3416873 | pubmed:pagination | 47-52 | lld:pubmed |
| pubmed-article:3416873 | pubmed:dateRevised | 2007-7-23 | lld:pubmed |
| pubmed-article:3416873 | pubmed:meshHeading | pubmed-meshheading:3416873-... | lld:pubmed |
| pubmed-article:3416873 | pubmed:meshHeading | pubmed-meshheading:3416873-... | lld:pubmed |
| pubmed-article:3416873 | pubmed:meshHeading | pubmed-meshheading:3416873-... | lld:pubmed |
| pubmed-article:3416873 | pubmed:meshHeading | pubmed-meshheading:3416873-... | lld:pubmed |
| pubmed-article:3416873 | pubmed:meshHeading | pubmed-meshheading:3416873-... | lld:pubmed |
| pubmed-article:3416873 | pubmed:meshHeading | pubmed-meshheading:3416873-... | lld:pubmed |
| pubmed-article:3416873 | pubmed:meshHeading | pubmed-meshheading:3416873-... | lld:pubmed |
| pubmed-article:3416873 | pubmed:meshHeading | pubmed-meshheading:3416873-... | lld:pubmed |
| pubmed-article:3416873 | pubmed:meshHeading | pubmed-meshheading:3416873-... | lld:pubmed |
| pubmed-article:3416873 | pubmed:meshHeading | pubmed-meshheading:3416873-... | lld:pubmed |
| pubmed-article:3416873 | pubmed:meshHeading | pubmed-meshheading:3416873-... | lld:pubmed |
| pubmed-article:3416873 | pubmed:meshHeading | pubmed-meshheading:3416873-... | lld:pubmed |
| pubmed-article:3416873 | pubmed:meshHeading | pubmed-meshheading:3416873-... | lld:pubmed |
| pubmed-article:3416873 | pubmed:year | 1988 | lld:pubmed |
| pubmed-article:3416873 | pubmed:articleTitle | The regulation of the cytoplasmic free Ca2+ concentration in aortic smooth muscle cells (A7r5 line) after stimulation by vasopressin and bombesin. | lld:pubmed |
| pubmed-article:3416873 | pubmed:affiliation | Centre de Biochimie, Centre National de la Recherche Scientifique, Nice, France. | lld:pubmed |
| pubmed-article:3416873 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:3416873 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:3416873 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:3416873 | lld:pubmed |
