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pubmed-article:3416035pubmed:abstractTextThe enthalpy change for the hydrolysis of phosphorylcreatine (PCr) by hydrochloric acid or by alkaline phosphatase was observed at 0, 25, and 37 degrees C. The value for delta H is -44 kJ mol-1 under alkaline, Mg2+-free conditions and is almost independent of temperature, ionic strength, and concentration of reactants. In muscle the reaction is accompanied by a transfer of protons from the buffers (largely histidine) to orthophosphate, release of Mg2+ from PCr, and binding of Mg2+ to orthophosphate. Measurements are reported of the heats of these processes. The calculated value of the overall heat of hydrolysis of PCr (including these processes) at pH 7, pMg 3 is -35 kJ mol-1.lld:pubmed
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pubmed-article:3416035pubmed:authorpubmed-author:ReillyP JPJlld:pubmed
pubmed-article:3416035pubmed:authorpubmed-author:WoledgeR CRClld:pubmed
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pubmed-article:3416035pubmed:dateRevised2009-11-18lld:pubmed
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pubmed-article:3416035pubmed:articleTitleMolar enthalpy change for hydrolysis of phosphorylcreatine under conditions in muscle cells.lld:pubmed
pubmed-article:3416035pubmed:affiliationDepartment of Physiology, University College London, United, Kingdom.lld:pubmed
pubmed-article:3416035pubmed:publicationTypeJournal Articlelld:pubmed
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