pubmed-article:3388031 | rdf:type | pubmed:Citation | lld:pubmed |
pubmed-article:3388031 | lifeskim:mentions | umls-concept:C0037224 | lld:lifeskim |
pubmed-article:3388031 | lifeskim:mentions | umls-concept:C0019707 | lld:lifeskim |
pubmed-article:3388031 | lifeskim:mentions | umls-concept:C0033684 | lld:lifeskim |
pubmed-article:3388031 | lifeskim:mentions | umls-concept:C0204727 | lld:lifeskim |
pubmed-article:3388031 | lifeskim:mentions | umls-concept:C0205409 | lld:lifeskim |
pubmed-article:3388031 | lifeskim:mentions | umls-concept:C1514468 | lld:lifeskim |
pubmed-article:3388031 | lifeskim:mentions | umls-concept:C0679622 | lld:lifeskim |
pubmed-article:3388031 | lifeskim:mentions | umls-concept:C1880022 | lld:lifeskim |
pubmed-article:3388031 | lifeskim:mentions | umls-concept:C0205314 | lld:lifeskim |
pubmed-article:3388031 | pubmed:issue | 4862 | lld:pubmed |
pubmed-article:3388031 | pubmed:dateCreated | 1988-8-3 | lld:pubmed |
pubmed-article:3388031 | pubmed:abstractText | A protein designated p14 was purified from a simian immunodeficiency virus (SIVMne) and was shown by amino acid sequence analysis to be nearly identical to the predicted translational product of a unique open reading frame (X-ORF) in the nucleotide sequences of SIVmac and human immunodeficiency virus type 2 (HIV-2). Thus the X-ORF is proven to be a new retroviral gene. The p14 is present in SIVMne in molar amounts equivalent to those of the gag proteins. This is the first example of a retrovirus that contains a substantial quantity of a viral protein that is not a product of the gag, pro, pol, or env genes. SIV p14 and its homolog in HIV-2 may function as nucleic acid binding proteins since purified p14 binds to single-stranded nucleic acids in vitro. Antisera to the purified protein detected p14 in SIVMne, SIVmac, and a homologous protein (16 kilodaltons) in HIV-2 but did not react with HIV-1. Diagnostic procedures based on this novel protein will distinguish between HIV-1 and HIV-2. | lld:pubmed |
pubmed-article:3388031 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:3388031 | pubmed:language | eng | lld:pubmed |
pubmed-article:3388031 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:3388031 | pubmed:citationSubset | IM | lld:pubmed |
pubmed-article:3388031 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:3388031 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:3388031 | pubmed:status | MEDLINE | lld:pubmed |
pubmed-article:3388031 | pubmed:month | Jul | lld:pubmed |
pubmed-article:3388031 | pubmed:issn | 0036-8075 | lld:pubmed |
pubmed-article:3388031 | pubmed:author | pubmed-author:BenvenisteR... | lld:pubmed |
pubmed-article:3388031 | pubmed:author | pubmed-author:OroszlanSS | lld:pubmed |
pubmed-article:3388031 | pubmed:author | pubmed-author:HendersonL... | lld:pubmed |
pubmed-article:3388031 | pubmed:author | pubmed-author:CopelandT DTD | lld:pubmed |
pubmed-article:3388031 | pubmed:author | pubmed-author:SowderR CRC | lld:pubmed |
pubmed-article:3388031 | pubmed:issnType | Print | lld:pubmed |
pubmed-article:3388031 | pubmed:day | 8 | lld:pubmed |
pubmed-article:3388031 | pubmed:volume | 241 | lld:pubmed |
pubmed-article:3388031 | pubmed:owner | NLM | lld:pubmed |
pubmed-article:3388031 | pubmed:authorsComplete | Y | lld:pubmed |
pubmed-article:3388031 | pubmed:pagination | 199-201 | lld:pubmed |
pubmed-article:3388031 | pubmed:dateRevised | 2007-11-14 | lld:pubmed |
pubmed-article:3388031 | pubmed:meshHeading | pubmed-meshheading:3388031-... | lld:pubmed |
pubmed-article:3388031 | pubmed:meshHeading | pubmed-meshheading:3388031-... | lld:pubmed |
pubmed-article:3388031 | pubmed:meshHeading | pubmed-meshheading:3388031-... | lld:pubmed |
pubmed-article:3388031 | pubmed:meshHeading | pubmed-meshheading:3388031-... | lld:pubmed |
pubmed-article:3388031 | pubmed:meshHeading | pubmed-meshheading:3388031-... | lld:pubmed |
pubmed-article:3388031 | pubmed:meshHeading | pubmed-meshheading:3388031-... | lld:pubmed |
pubmed-article:3388031 | pubmed:year | 1988 | lld:pubmed |
pubmed-article:3388031 | pubmed:articleTitle | Isolation and characterization of a novel protein (X-ORF product) from SIV and HIV-2. | lld:pubmed |
pubmed-article:3388031 | pubmed:affiliation | Bionetics Research, Inc., National Cancer Institute, Frederick, MD 21701. | lld:pubmed |
pubmed-article:3388031 | pubmed:publicationType | Journal Article | lld:pubmed |
pubmed-article:3388031 | pubmed:publicationType | Research Support, U.S. Gov't, P.H.S. | lld:pubmed |
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