Statements in which the resource exists.
SubjectPredicateObjectContext
pubmed-article:3371585rdf:typepubmed:Citationlld:pubmed
pubmed-article:3371585lifeskim:mentionsumls-concept:C0392419lld:lifeskim
pubmed-article:3371585lifeskim:mentionsumls-concept:C0424295lld:lifeskim
pubmed-article:3371585lifeskim:mentionsumls-concept:C0040880lld:lifeskim
pubmed-article:3371585lifeskim:mentionsumls-concept:C0205263lld:lifeskim
pubmed-article:3371585lifeskim:mentionsumls-concept:C0076996lld:lifeskim
pubmed-article:3371585pubmed:issue3lld:pubmed
pubmed-article:3371585pubmed:dateCreated1988-7-14lld:pubmed
pubmed-article:3371585pubmed:abstractTextTriadimefon is an agriculturally important triazole fungicide. The present experiments were conducted to characterize the effects of triadimefon on a measure of motor activity. Dosage-effect, time-effect, and the effect of repeated dosing (7 days) were determined following triadimefon exposure. Male Long Evans hooded rats, approximately 70 days old, received triadimefon po in 2.0 ml/kg corn oil. Motor activity testing was conducted for 1 hr in figure-eight mazes. For the dosage-effect determination, triadimefon (50-400 mg/kg) was administered 1 hr prior to testing. In the time-course study, triadimefon (200 mg/kg) was administered either 0.5, 1, 2, 4, 8, or 24 hr prior to testing. In the repeated dosing experiment animals received triadimefon (100 mg/kg) daily for 7 days and were tested 24 hr after the last exposure. Triadimefon produced significant hyperactivity following dosages of 100 and 200 mg/kg. This hyperactivity was rapid in both onset (0.5 hr) and recovery (8.0 hr). Repeated dosing with 100 mg/kg/day revealed no cumulative effects nor tolerance. These results indicate that triadimefon produces a transient hyperactivity at dosages 17 to 33% of the reported LD50.lld:pubmed
pubmed-article:3371585pubmed:languageenglld:pubmed
pubmed-article:3371585pubmed:journalhttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:3371585pubmed:citationSubsetIMlld:pubmed
pubmed-article:3371585pubmed:chemicalhttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:3371585pubmed:chemicalhttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:3371585pubmed:chemicalhttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:3371585pubmed:statusMEDLINElld:pubmed
pubmed-article:3371585pubmed:monthAprlld:pubmed
pubmed-article:3371585pubmed:issn0272-0590lld:pubmed
pubmed-article:3371585pubmed:authorpubmed-author:ReiterL WLWlld:pubmed
pubmed-article:3371585pubmed:authorpubmed-author:CroftonK MKMlld:pubmed
pubmed-article:3371585pubmed:authorpubmed-author:BoncekV MVMlld:pubmed
pubmed-article:3371585pubmed:issnTypePrintlld:pubmed
pubmed-article:3371585pubmed:volume10lld:pubmed
pubmed-article:3371585pubmed:ownerNLMlld:pubmed
pubmed-article:3371585pubmed:authorsCompleteYlld:pubmed
pubmed-article:3371585pubmed:pagination459-65lld:pubmed
pubmed-article:3371585pubmed:dateRevised2003-11-14lld:pubmed
pubmed-article:3371585pubmed:meshHeadingpubmed-meshheading:3371585-...lld:pubmed
pubmed-article:3371585pubmed:meshHeadingpubmed-meshheading:3371585-...lld:pubmed
pubmed-article:3371585pubmed:meshHeadingpubmed-meshheading:3371585-...lld:pubmed
pubmed-article:3371585pubmed:meshHeadingpubmed-meshheading:3371585-...lld:pubmed
pubmed-article:3371585pubmed:meshHeadingpubmed-meshheading:3371585-...lld:pubmed
pubmed-article:3371585pubmed:meshHeadingpubmed-meshheading:3371585-...lld:pubmed
pubmed-article:3371585pubmed:meshHeadingpubmed-meshheading:3371585-...lld:pubmed
pubmed-article:3371585pubmed:year1988lld:pubmed
pubmed-article:3371585pubmed:articleTitleHyperactivity induced by triadimefon, a triazole fungicide.lld:pubmed
pubmed-article:3371585pubmed:affiliationNeurotoxicology Division, Environmental Protection Agency, Research Triangle Park, North Carolina 27711.lld:pubmed
pubmed-article:3371585pubmed:publicationTypeJournal Articlelld:pubmed