| pubmed-article:3345562 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:3345562 | lifeskim:mentions | umls-concept:C0020792 | lld:lifeskim |
| pubmed-article:3345562 | lifeskim:mentions | umls-concept:C0013935 | lld:lifeskim |
| pubmed-article:3345562 | lifeskim:mentions | umls-concept:C0521449 | lld:lifeskim |
| pubmed-article:3345562 | lifeskim:mentions | umls-concept:C0017337 | lld:lifeskim |
| pubmed-article:3345562 | lifeskim:mentions | umls-concept:C0475264 | lld:lifeskim |
| pubmed-article:3345562 | lifeskim:mentions | umls-concept:C0162610 | lld:lifeskim |
| pubmed-article:3345562 | lifeskim:mentions | umls-concept:C1546857 | lld:lifeskim |
| pubmed-article:3345562 | lifeskim:mentions | umls-concept:C1556066 | lld:lifeskim |
| pubmed-article:3345562 | lifeskim:mentions | umls-concept:C1619636 | lld:lifeskim |
| pubmed-article:3345562 | lifeskim:mentions | umls-concept:C1514873 | lld:lifeskim |
| pubmed-article:3345562 | pubmed:issue | 3 | lld:pubmed |
| pubmed-article:3345562 | pubmed:dateCreated | 1988-4-19 | lld:pubmed |
| pubmed-article:3345562 | pubmed:abstractText | We have isolated and analyzed eight strict maternal effect mutations identifying four genes, par-1, par-2, par-3, and par-4, required for cytoplasmic localization in early embryos of the nematode C. elegans. Mutations in these genes lead to defects in cleavage patterns, timing of cleavages, and localization of germ line-specific P granules. Four mutations in par-1 and par-4 are fully expressed maternal effect lethal mutations; all embryos from mothers homozygous for these mutations arrest as amorphous masses of differentiated cells but are specifically lacking intestinal cells. Four mutations in par-2, par-3, and par-4 are incompletely expressed maternal effect lethal mutations and are also grandchildless; some embryos from homozygous mothers survive and grow to become infertile adults due to absence of functional germ cells. We propose that all of these defects result from the failure of a maternally encoded system for intracellular localization in early embryos. | lld:pubmed |
| pubmed-article:3345562 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:3345562 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:3345562 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:3345562 | pubmed:language | eng | lld:pubmed |
| pubmed-article:3345562 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:3345562 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:3345562 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:3345562 | pubmed:month | Feb | lld:pubmed |
| pubmed-article:3345562 | pubmed:issn | 0092-8674 | lld:pubmed |
| pubmed-article:3345562 | pubmed:author | pubmed-author:KemphuesK JKJ | lld:pubmed |
| pubmed-article:3345562 | pubmed:author | pubmed-author:MortonD GDG | lld:pubmed |
| pubmed-article:3345562 | pubmed:author | pubmed-author:PriessJ RJR | lld:pubmed |
| pubmed-article:3345562 | pubmed:author | pubmed-author:ChengN SNS | lld:pubmed |
| pubmed-article:3345562 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:3345562 | pubmed:day | 12 | lld:pubmed |
| pubmed-article:3345562 | pubmed:volume | 52 | lld:pubmed |
| pubmed-article:3345562 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:3345562 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:3345562 | pubmed:pagination | 311-20 | lld:pubmed |
| pubmed-article:3345562 | pubmed:dateRevised | 2007-11-14 | lld:pubmed |
| pubmed-article:3345562 | pubmed:meshHeading | pubmed-meshheading:3345562-... | lld:pubmed |
| pubmed-article:3345562 | pubmed:meshHeading | pubmed-meshheading:3345562-... | lld:pubmed |
| pubmed-article:3345562 | pubmed:meshHeading | pubmed-meshheading:3345562-... | lld:pubmed |
| pubmed-article:3345562 | pubmed:meshHeading | pubmed-meshheading:3345562-... | lld:pubmed |
| pubmed-article:3345562 | pubmed:meshHeading | pubmed-meshheading:3345562-... | lld:pubmed |
| pubmed-article:3345562 | pubmed:meshHeading | pubmed-meshheading:3345562-... | lld:pubmed |
| pubmed-article:3345562 | pubmed:meshHeading | pubmed-meshheading:3345562-... | lld:pubmed |
| pubmed-article:3345562 | pubmed:meshHeading | pubmed-meshheading:3345562-... | lld:pubmed |
| pubmed-article:3345562 | pubmed:meshHeading | pubmed-meshheading:3345562-... | lld:pubmed |
| pubmed-article:3345562 | pubmed:meshHeading | pubmed-meshheading:3345562-... | lld:pubmed |
| pubmed-article:3345562 | pubmed:meshHeading | pubmed-meshheading:3345562-... | lld:pubmed |
| pubmed-article:3345562 | pubmed:year | 1988 | lld:pubmed |
| pubmed-article:3345562 | pubmed:articleTitle | Identification of genes required for cytoplasmic localization in early C. elegans embryos. | lld:pubmed |
| pubmed-article:3345562 | pubmed:affiliation | Section of Genetics and Development Cornell University Ithaca, New York 14853. | lld:pubmed |
| pubmed-article:3345562 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:3345562 | pubmed:publicationType | Research Support, U.S. Gov't, P.H.S. | lld:pubmed |
| pubmed-article:3345562 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:3345562 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:3345562 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:3345562 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:3345562 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:3345562 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:3345562 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:3345562 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:3345562 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:3345562 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:3345562 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:3345562 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:3345562 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:3345562 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:3345562 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:3345562 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:3345562 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:3345562 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:3345562 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:3345562 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:3345562 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:3345562 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:3345562 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:3345562 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:3345562 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:3345562 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:3345562 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:3345562 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:3345562 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:3345562 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:3345562 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:3345562 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:3345562 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:3345562 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:3345562 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:3345562 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:3345562 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:3345562 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:3345562 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:3345562 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:3345562 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:3345562 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:3345562 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:3345562 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:3345562 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:3345562 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:3345562 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:3345562 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:3345562 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:3345562 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:3345562 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:3345562 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:3345562 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:3345562 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:3345562 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:3345562 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:3345562 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:3345562 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:3345562 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:3345562 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:3345562 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:3345562 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:3345562 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:3345562 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:3345562 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:3345562 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:3345562 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:3345562 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:3345562 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:3345562 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:3345562 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:3345562 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:3345562 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:3345562 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:3345562 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:3345562 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:3345562 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:3345562 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:3345562 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:3345562 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:3345562 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:3345562 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:3345562 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:3345562 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:3345562 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:3345562 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:3345562 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:3345562 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:3345562 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:3345562 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:3345562 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:3345562 | lld:pubmed |
