pubmed-article:3345313 | rdf:type | pubmed:Citation | lld:pubmed |
pubmed-article:3345313 | lifeskim:mentions | umls-concept:C0003392 | lld:lifeskim |
pubmed-article:3345313 | lifeskim:mentions | umls-concept:C0007125 | lld:lifeskim |
pubmed-article:3345313 | lifeskim:mentions | umls-concept:C0025519 | lld:lifeskim |
pubmed-article:3345313 | lifeskim:mentions | umls-concept:C0431085 | lld:lifeskim |
pubmed-article:3345313 | lifeskim:mentions | umls-concept:C0014994 | lld:lifeskim |
pubmed-article:3345313 | lifeskim:mentions | umls-concept:C0017950 | lld:lifeskim |
pubmed-article:3345313 | lifeskim:mentions | umls-concept:C0441655 | lld:lifeskim |
pubmed-article:3345313 | pubmed:issue | 1 | lld:pubmed |
pubmed-article:3345313 | pubmed:dateCreated | 1988-4-11 | lld:pubmed |
pubmed-article:3345313 | pubmed:abstractText | Ehrlich ascites tumor cells were incubated in vitro with rac-1-O-[1'-14C]octadecyl-2-O-methylglycero-3-beta-D-glucopyranosi de for 24 h. The potentially antineoplastic ether glycolipid was rapidly metabolized by the cells to radioactive 1-O-octadecyl-2-O-methylglycerol (70 pmol/10(6) cells per h) and further acylated to 1-O-octadecyl-2-O-methyl-3-acylglycerols. Incubation of Ehrlich ascites cells with synthetic rac-1-O-[1'-14C]octadecyl-2-O-methyl-3-palmitoylglycerol showed that this metabolite is reconverted by deacylation to 14C-labeled 1-O-octadecyl-2-O-methylglycerol. The latter compound or a metabolite derived therefrom may be the 'toxic principle' of both the ether glyceroglycolipids and ether glycerophospholipids having a 1-O-alkyl-2-O-methylglyceryl moiety, as suggested by Unger et al. (J. Natl. Cancer Inst. 78 (1987) 219-222). | lld:pubmed |
pubmed-article:3345313 | pubmed:language | eng | lld:pubmed |
pubmed-article:3345313 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:3345313 | pubmed:citationSubset | IM | lld:pubmed |
pubmed-article:3345313 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:3345313 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:3345313 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:3345313 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:3345313 | pubmed:status | MEDLINE | lld:pubmed |
pubmed-article:3345313 | pubmed:month | Mar | lld:pubmed |
pubmed-article:3345313 | pubmed:issn | 0006-3002 | lld:pubmed |
pubmed-article:3345313 | pubmed:author | pubmed-author:WeberNN | lld:pubmed |
pubmed-article:3345313 | pubmed:author | pubmed-author:BenningHH | lld:pubmed |
pubmed-article:3345313 | pubmed:issnType | Print | lld:pubmed |
pubmed-article:3345313 | pubmed:day | 4 | lld:pubmed |
pubmed-article:3345313 | pubmed:volume | 959 | lld:pubmed |
pubmed-article:3345313 | pubmed:owner | NLM | lld:pubmed |
pubmed-article:3345313 | pubmed:authorsComplete | Y | lld:pubmed |
pubmed-article:3345313 | pubmed:pagination | 91-4 | lld:pubmed |
pubmed-article:3345313 | pubmed:dateRevised | 2006-11-15 | lld:pubmed |
pubmed-article:3345313 | pubmed:meshHeading | pubmed-meshheading:3345313-... | lld:pubmed |
pubmed-article:3345313 | pubmed:meshHeading | pubmed-meshheading:3345313-... | lld:pubmed |
pubmed-article:3345313 | pubmed:meshHeading | pubmed-meshheading:3345313-... | lld:pubmed |
pubmed-article:3345313 | pubmed:meshHeading | pubmed-meshheading:3345313-... | lld:pubmed |
pubmed-article:3345313 | pubmed:meshHeading | pubmed-meshheading:3345313-... | lld:pubmed |
pubmed-article:3345313 | pubmed:meshHeading | pubmed-meshheading:3345313-... | lld:pubmed |
pubmed-article:3345313 | pubmed:meshHeading | pubmed-meshheading:3345313-... | lld:pubmed |
pubmed-article:3345313 | pubmed:meshHeading | pubmed-meshheading:3345313-... | lld:pubmed |
pubmed-article:3345313 | pubmed:year | 1988 | lld:pubmed |
pubmed-article:3345313 | pubmed:articleTitle | Metabolism of ether glycolipids with potentially antineoplastic activity by Ehrlich ascites tumor cells. | lld:pubmed |
pubmed-article:3345313 | pubmed:affiliation | Bundesanstalt für Fettforschung, Institut für Biochemie und Technologie, H.P. Kaufmann-Institut, Münster, F.R.G. | lld:pubmed |
pubmed-article:3345313 | pubmed:publicationType | Journal Article | lld:pubmed |
pubmed-article:3345313 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:3345313 | lld:pubmed |