| pubmed-article:3323889 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:3323889 | lifeskim:mentions | umls-concept:C0029005 | lld:lifeskim |
| pubmed-article:3323889 | lifeskim:mentions | umls-concept:C0033634 | lld:lifeskim |
| pubmed-article:3323889 | lifeskim:mentions | umls-concept:C0205245 | lld:lifeskim |
| pubmed-article:3323889 | lifeskim:mentions | umls-concept:C1704632 | lld:lifeskim |
| pubmed-article:3323889 | lifeskim:mentions | umls-concept:C0871261 | lld:lifeskim |
| pubmed-article:3323889 | lifeskim:mentions | umls-concept:C0018446 | lld:lifeskim |
| pubmed-article:3323889 | lifeskim:mentions | umls-concept:C2911692 | lld:lifeskim |
| pubmed-article:3323889 | lifeskim:mentions | umls-concept:C1706817 | lld:lifeskim |
| pubmed-article:3323889 | lifeskim:mentions | umls-concept:C1314939 | lld:lifeskim |
| pubmed-article:3323889 | pubmed:issue | 11 | lld:pubmed |
| pubmed-article:3323889 | pubmed:dateCreated | 1988-3-8 | lld:pubmed |
| pubmed-article:3323889 | pubmed:abstractText | Microinjection of purified protein kinase C (PKC) into Swiss 3T3 fibroblasts pretreated with the phorbol ester phorbol-12,13-dibutyrate restores the mitogenic response of the cells to phorbol-12,13-dibutyrate (G. Pasti, J.C. Lacal, B.S. Warren, S.A. Aaronson, and P.M. Blumberg, Nature [London] 324:375-377, 1986). Our present studies demonstrate that the mitogenic activity of the H-ras oncogene in H-ras p21-microinjected quiescent cells is markedly reduced under conditions in which PKC is downregulated by chronic phorbol ester treatment. The ability to reconstitute the mitogenic response upon microinjection of both H-ras p21 and PKC implies involvement of functional PKC in the mitogenic activity of the H-ras oncogene product. | lld:pubmed |
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| pubmed-article:3323889 | pubmed:language | eng | lld:pubmed |
| pubmed-article:3323889 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:3323889 | pubmed:citationSubset | IM | lld:pubmed |
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| pubmed-article:3323889 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:3323889 | pubmed:month | Nov | lld:pubmed |
| pubmed-article:3323889 | pubmed:issn | 0270-7306 | lld:pubmed |
| pubmed-article:3323889 | pubmed:author | pubmed-author:AaronsonS ASA | lld:pubmed |
| pubmed-article:3323889 | pubmed:author | pubmed-author:BlumbergP MPM | lld:pubmed |
| pubmed-article:3323889 | pubmed:author | pubmed-author:WarrenB SBS | lld:pubmed |
| pubmed-article:3323889 | pubmed:author | pubmed-author:FlemingT PTP | lld:pubmed |
| pubmed-article:3323889 | pubmed:author | pubmed-author:LacalJ CJC | lld:pubmed |
| pubmed-article:3323889 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:3323889 | pubmed:volume | 7 | lld:pubmed |
| pubmed-article:3323889 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:3323889 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:3323889 | pubmed:pagination | 4146-9 | lld:pubmed |
| pubmed-article:3323889 | pubmed:dateRevised | 2009-11-18 | lld:pubmed |
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| pubmed-article:3323889 | pubmed:year | 1987 | lld:pubmed |
| pubmed-article:3323889 | pubmed:articleTitle | Involvement of functional protein kinase C in the mitogenic response to the H-ras oncogene product. | lld:pubmed |
| pubmed-article:3323889 | pubmed:affiliation | Laboratory of Cellular and Molecular Biology, National Cancer Institute, Bethesda, Maryland 20892. | lld:pubmed |
| pubmed-article:3323889 | pubmed:publicationType | Journal Article | lld:pubmed |
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