| pubmed-article:3306411 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:3306411 | lifeskim:mentions | umls-concept:C0035366 | lld:lifeskim |
| pubmed-article:3306411 | lifeskim:mentions | umls-concept:C0030940 | lld:lifeskim |
| pubmed-article:3306411 | lifeskim:mentions | umls-concept:C0026349 | lld:lifeskim |
| pubmed-article:3306411 | pubmed:issue | 6137 | lld:pubmed |
| pubmed-article:3306411 | pubmed:dateCreated | 1987-10-22 | lld:pubmed |
| pubmed-article:3306411 | pubmed:abstractText | In many retroviruses the 5' end of the pol gene codes for a protease vital for the processing of the gag polyprotein into the separate core proteins. In some viruses this protease is encoded at the 3' end of the gag gene, or between the gag and pol genes in a different reading frame to either. A sequence, Asp-Thr-Gly, which is conserved in retroviral proteases is also conserved in the active sites of aspartic proteases, an observation which has led to the suggestion that the retroviral proteases could belong to this family. We have examined the sequences of the aspartic and retroviral protease families, using pattern-recognition, structure prediction and molecular modelling techniques, and conclude that the viral protease sequences probably correspond to a single domain of an aspartic protease and may function in a dimeric form. We have constructed a model of the pol-protease of human immunodeficiency virus 1 (HIV-1) to test this hypothesis. | lld:pubmed |
| pubmed-article:3306411 | pubmed:language | eng | lld:pubmed |
| pubmed-article:3306411 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:3306411 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:3306411 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:3306411 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:3306411 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:3306411 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:3306411 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:3306411 | pubmed:issn | 0028-0836 | lld:pubmed |
| pubmed-article:3306411 | pubmed:author | pubmed-author:TaylorW RWR | lld:pubmed |
| pubmed-article:3306411 | pubmed:author | pubmed-author:PearlL HLH | lld:pubmed |
| pubmed-article:3306411 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:3306411 | pubmed:volume | 329 | lld:pubmed |
| pubmed-article:3306411 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:3306411 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:3306411 | pubmed:pagination | 351-4 | lld:pubmed |
| pubmed-article:3306411 | pubmed:dateRevised | 2009-11-19 | lld:pubmed |
| pubmed-article:3306411 | pubmed:meshHeading | pubmed-meshheading:3306411-... | lld:pubmed |
| pubmed-article:3306411 | pubmed:meshHeading | pubmed-meshheading:3306411-... | lld:pubmed |
| pubmed-article:3306411 | pubmed:meshHeading | pubmed-meshheading:3306411-... | lld:pubmed |
| pubmed-article:3306411 | pubmed:meshHeading | pubmed-meshheading:3306411-... | lld:pubmed |
| pubmed-article:3306411 | pubmed:meshHeading | pubmed-meshheading:3306411-... | lld:pubmed |
| pubmed-article:3306411 | pubmed:meshHeading | pubmed-meshheading:3306411-... | lld:pubmed |
| pubmed-article:3306411 | pubmed:meshHeading | pubmed-meshheading:3306411-... | lld:pubmed |
| pubmed-article:3306411 | pubmed:meshHeading | pubmed-meshheading:3306411-... | lld:pubmed |
| pubmed-article:3306411 | pubmed:meshHeading | pubmed-meshheading:3306411-... | lld:pubmed |
| pubmed-article:3306411 | pubmed:meshHeading | pubmed-meshheading:3306411-... | lld:pubmed |
| pubmed-article:3306411 | pubmed:articleTitle | A structural model for the retroviral proteases. | lld:pubmed |
| pubmed-article:3306411 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:3306411 | pubmed:publicationType | Comparative Study | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:3306411 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:3306411 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:3306411 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:3306411 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:3306411 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:3306411 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:3306411 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:3306411 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:3306411 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:3306411 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:3306411 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:3306411 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:3306411 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:3306411 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:3306411 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:3306411 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:3306411 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:3306411 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:3306411 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:3306411 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:3306411 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:3306411 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:3306411 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:3306411 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:3306411 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:3306411 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:3306411 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:3306411 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:3306411 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:3306411 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:3306411 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:3306411 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:3306411 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:3306411 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:3306411 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:3306411 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:3306411 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:3306411 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:3306411 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:3306411 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:3306411 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:3306411 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:3306411 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:3306411 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:3306411 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:3306411 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:3306411 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:3306411 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:3306411 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:3306411 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:3306411 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:3306411 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:3306411 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:3306411 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:3306411 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:3306411 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:3306411 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:3306411 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:3306411 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:3306411 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:3306411 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:3306411 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:3306411 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:3306411 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:3306411 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:3306411 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:3306411 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:3306411 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:3306411 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:3306411 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:3306411 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:3306411 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:3306411 | lld:pubmed |
