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pubmed-article:3286699pubmed:abstractTextIntramammary leucocytosis was induced by injection of Escherichia coli endotoxin via the teat canal in three lactating Holstein cows. Concentrations of alpha-lactalbumin and casein in blood serum were measured, and somatic cell concentration and yield and composition of milk were determined. Endotoxin injection elicited mean increases of 100-fold in somatic cell concentration and 50% in protein concentration, whereas milk yield declined 5-fold and lactose concentration was halved. Concentrations of alpha-lactalbumin and casein in blood rose from 80 to 1909 and 0 to 1231 ng/ml, respectively. By 96 h postinjection, all variables were approximately equal to those preinjection. In a second study, concentration of alpha-lactalbumin was determined in blood of lactating cows in two herds (n = 332) and related to milk somatic cell count. Concentrations of alpha-lactalbumin in blood were correlated with somatic cell counts (r = .60). Mean concentrations of alpha-lactalbumin increased with increasing cell count even at low somatic cell concentrations (25 to 250 X 10(3)). Concentrations of milk proteins in blood serum apparently reflect competency of the blood-milk barrier and may therefore yield an indirect measure of udder health.lld:pubmed
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pubmed-article:3286699pubmed:pagination826-34lld:pubmed
pubmed-article:3286699pubmed:dateRevised2006-11-15lld:pubmed
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pubmed-article:3286699pubmed:year1988lld:pubmed
pubmed-article:3286699pubmed:articleTitleRelationship of milk proteins in blood with somatic cell counts in milk of dairy cows.lld:pubmed
pubmed-article:3286699pubmed:affiliationDepartment of Dairy Science, Virginia Polytechnic Institute and State University, Blacksburg 24061.lld:pubmed
pubmed-article:3286699pubmed:publicationTypeJournal Articlelld:pubmed
pubmed-article:3286699pubmed:publicationTypeResearch Support, U.S. Gov't, Non-P.H.S.lld:pubmed