| pubmed-article:3282486 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:3282486 | lifeskim:mentions | umls-concept:C0086418 | lld:lifeskim |
| pubmed-article:3282486 | lifeskim:mentions | umls-concept:C0006826 | lld:lifeskim |
| pubmed-article:3282486 | lifeskim:mentions | umls-concept:C0038402 | lld:lifeskim |
| pubmed-article:3282486 | lifeskim:mentions | umls-concept:C0205208 | lld:lifeskim |
| pubmed-article:3282486 | lifeskim:mentions | umls-concept:C0001551 | lld:lifeskim |
| pubmed-article:3282486 | lifeskim:mentions | umls-concept:C1280500 | lld:lifeskim |
| pubmed-article:3282486 | lifeskim:mentions | umls-concept:C0205276 | lld:lifeskim |
| pubmed-article:3282486 | lifeskim:mentions | umls-concept:C1441616 | lld:lifeskim |
| pubmed-article:3282486 | lifeskim:mentions | umls-concept:C2603343 | lld:lifeskim |
| pubmed-article:3282486 | lifeskim:mentions | umls-concept:C0918027 | lld:lifeskim |
| pubmed-article:3282486 | pubmed:issue | 5 | lld:pubmed |
| pubmed-article:3282486 | pubmed:dateCreated | 1988-5-24 | lld:pubmed |
| pubmed-article:3282486 | pubmed:abstractText | Immunocytochemical techniques were used to clarify the local inhibitory effects of a streptococcal immunopotentiator, OK-432, against solid malignant tumor growth. Natural killer (NK) cells and fibronectin were chosen as immunostaining markers to demonstrate the antitumor effects. Immunocytochemical staining was performed by the avidin-biotin-peroxidase complex method. These investigations demonstrated that (1) local administration of OK-432 seems to promote a marked induction of NK cells and fibroblasts around or entering into the cancerous lesions and (2) the cancer cell-killing effect of NK cells and the fibronectin-enriched stromal reaction augmented by the injection of OK-432 suggest at least the possibility of protection against neoplastic growth with invasion and the spread of distant or nodal metastases of solid carcinomas. | lld:pubmed |
| pubmed-article:3282486 | pubmed:language | eng | lld:pubmed |
| pubmed-article:3282486 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:3282486 | pubmed:citationSubset | AIM | lld:pubmed |
| pubmed-article:3282486 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:3282486 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:3282486 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:3282486 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:3282486 | pubmed:month | May | lld:pubmed |
| pubmed-article:3282486 | pubmed:issn | 0003-9985 | lld:pubmed |
| pubmed-article:3282486 | pubmed:author | pubmed-author:NagataTT | lld:pubmed |
| pubmed-article:3282486 | pubmed:author | pubmed-author:SugenoyaAA | lld:pubmed |
| pubmed-article:3282486 | pubmed:author | pubmed-author:IidaFF | lld:pubmed |
| pubmed-article:3282486 | pubmed:author | pubmed-author:AdachiWW | lld:pubmed |
| pubmed-article:3282486 | pubmed:author | pubmed-author:UsudaNN | lld:pubmed |
| pubmed-article:3282486 | pubmed:author | pubmed-author:KanekoGG | lld:pubmed |
| pubmed-article:3282486 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:3282486 | pubmed:volume | 112 | lld:pubmed |
| pubmed-article:3282486 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:3282486 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:3282486 | pubmed:pagination | 545-9 | lld:pubmed |
| pubmed-article:3282486 | pubmed:dateRevised | 2011-11-17 | lld:pubmed |
| pubmed-article:3282486 | pubmed:meshHeading | pubmed-meshheading:3282486-... | lld:pubmed |
| pubmed-article:3282486 | pubmed:meshHeading | pubmed-meshheading:3282486-... | lld:pubmed |
| pubmed-article:3282486 | pubmed:meshHeading | pubmed-meshheading:3282486-... | lld:pubmed |
| pubmed-article:3282486 | pubmed:meshHeading | pubmed-meshheading:3282486-... | lld:pubmed |
| pubmed-article:3282486 | pubmed:meshHeading | pubmed-meshheading:3282486-... | lld:pubmed |
| pubmed-article:3282486 | pubmed:meshHeading | pubmed-meshheading:3282486-... | lld:pubmed |
| pubmed-article:3282486 | pubmed:meshHeading | pubmed-meshheading:3282486-... | lld:pubmed |
| pubmed-article:3282486 | pubmed:meshHeading | pubmed-meshheading:3282486-... | lld:pubmed |
| pubmed-article:3282486 | pubmed:meshHeading | pubmed-meshheading:3282486-... | lld:pubmed |
| pubmed-article:3282486 | pubmed:meshHeading | pubmed-meshheading:3282486-... | lld:pubmed |
| pubmed-article:3282486 | pubmed:meshHeading | pubmed-meshheading:3282486-... | lld:pubmed |
| pubmed-article:3282486 | pubmed:meshHeading | pubmed-meshheading:3282486-... | lld:pubmed |
| pubmed-article:3282486 | pubmed:meshHeading | pubmed-meshheading:3282486-... | lld:pubmed |
| pubmed-article:3282486 | pubmed:year | 1988 | lld:pubmed |
| pubmed-article:3282486 | pubmed:articleTitle | Immunohistochemical studies on local antitumor effects of streptococcal immunopotentiator, OK-432, in human solid malignant tumors. | lld:pubmed |
| pubmed-article:3282486 | pubmed:affiliation | Department of Surgery, Shinshu University School of Medicine, Matsumoto, Japan. | lld:pubmed |
| pubmed-article:3282486 | pubmed:publicationType | Journal Article | lld:pubmed |
