| pubmed-article:3279818 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:3279818 | lifeskim:mentions | umls-concept:C0007600 | lld:lifeskim |
| pubmed-article:3279818 | lifeskim:mentions | umls-concept:C0014597 | lld:lifeskim |
| pubmed-article:3279818 | lifeskim:mentions | umls-concept:C0022646 | lld:lifeskim |
| pubmed-article:3279818 | lifeskim:mentions | umls-concept:C0005528 | lld:lifeskim |
| pubmed-article:3279818 | lifeskim:mentions | umls-concept:C0076252 | lld:lifeskim |
| pubmed-article:3279818 | pubmed:issue | 3 Pt 2 | lld:pubmed |
| pubmed-article:3279818 | pubmed:dateCreated | 1988-4-19 | lld:pubmed |
| pubmed-article:3279818 | pubmed:abstractText | We investigated whether the LLC-PK1 epithelial cell line (which shows many characteristics of proximal tubular cells) also is capable of transporting an organic ion. Suspended LLC-PK1 cells accumulated tetraethylammonium (TEA). The uptake showed characteristics of a facilitated mechanism; TEA uptake was saturable and temperature-dependent and was inhibited by other organic cations. Quinine and mepiperphenidol were the most potent inhibitors, whereas N1-methylnicotinamide and morphine inhibited the transport system only slightly at doses of 10(-3) M. Basolateral-to-apical TEA flux through LLC-PK1 monolayers was five to six times larger than that of mannitol, a nontransported compound, whereas apical-to-basolateral TEA and mannitol fluxes were equal. Only the basolateral-to-apical TEA flux was inhibited by quinine. Under similar experimental conditions, no transport of p-aminohippuric acid was observed. It is concluded that LLC-PK1 cells are able to transport TEA, as do cells of the proximal tubule. | lld:pubmed |
| pubmed-article:3279818 | pubmed:language | eng | lld:pubmed |
| pubmed-article:3279818 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:3279818 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:3279818 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:3279818 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:3279818 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:3279818 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:3279818 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:3279818 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:3279818 | pubmed:month | Mar | lld:pubmed |
| pubmed-article:3279818 | pubmed:issn | 0002-9513 | lld:pubmed |
| pubmed-article:3279818 | pubmed:author | pubmed-author:Roch-RamelFF | lld:pubmed |
| pubmed-article:3279818 | pubmed:author | pubmed-author:FauthCC | lld:pubmed |
| pubmed-article:3279818 | pubmed:author | pubmed-author:RossierBB | lld:pubmed |
| pubmed-article:3279818 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:3279818 | pubmed:volume | 254 | lld:pubmed |
| pubmed-article:3279818 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:3279818 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:3279818 | pubmed:pagination | F351-7 | lld:pubmed |
| pubmed-article:3279818 | pubmed:dateRevised | 2006-11-15 | lld:pubmed |
| pubmed-article:3279818 | pubmed:meshHeading | pubmed-meshheading:3279818-... | lld:pubmed |
| pubmed-article:3279818 | pubmed:meshHeading | pubmed-meshheading:3279818-... | lld:pubmed |
| pubmed-article:3279818 | pubmed:meshHeading | pubmed-meshheading:3279818-... | lld:pubmed |
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| pubmed-article:3279818 | pubmed:meshHeading | pubmed-meshheading:3279818-... | lld:pubmed |
| pubmed-article:3279818 | pubmed:meshHeading | pubmed-meshheading:3279818-... | lld:pubmed |
| pubmed-article:3279818 | pubmed:meshHeading | pubmed-meshheading:3279818-... | lld:pubmed |
| pubmed-article:3279818 | pubmed:meshHeading | pubmed-meshheading:3279818-... | lld:pubmed |
| pubmed-article:3279818 | pubmed:meshHeading | pubmed-meshheading:3279818-... | lld:pubmed |
| pubmed-article:3279818 | pubmed:meshHeading | pubmed-meshheading:3279818-... | lld:pubmed |
| pubmed-article:3279818 | pubmed:meshHeading | pubmed-meshheading:3279818-... | lld:pubmed |
| pubmed-article:3279818 | pubmed:meshHeading | pubmed-meshheading:3279818-... | lld:pubmed |
| pubmed-article:3279818 | pubmed:year | 1988 | lld:pubmed |
| pubmed-article:3279818 | pubmed:articleTitle | Transport of tetraethylammonium by a kidney epithelial cell line (LLC-PK1). | lld:pubmed |
| pubmed-article:3279818 | pubmed:affiliation | Institut de Pharmacologie de l'Université de Lausanne, Switzerland. | lld:pubmed |
| pubmed-article:3279818 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:3279818 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:3279818 | lld:pubmed |
