pubmed-article:3264007 | rdf:type | pubmed:Citation | lld:pubmed |
pubmed-article:3264007 | lifeskim:mentions | umls-concept:C1511362 | lld:lifeskim |
pubmed-article:3264007 | lifeskim:mentions | umls-concept:C1511363 | lld:lifeskim |
pubmed-article:3264007 | lifeskim:mentions | umls-concept:C0039194 | lld:lifeskim |
pubmed-article:3264007 | lifeskim:mentions | umls-concept:C0814999 | lld:lifeskim |
pubmed-article:3264007 | lifeskim:mentions | umls-concept:C0017082 | lld:lifeskim |
pubmed-article:3264007 | lifeskim:mentions | umls-concept:C1707455 | lld:lifeskim |
pubmed-article:3264007 | pubmed:issue | 6 | lld:pubmed |
pubmed-article:3264007 | pubmed:dateCreated | 1989-1-6 | lld:pubmed |
pubmed-article:3264007 | pubmed:abstractText | Gangliosides have been prepared from resting murine thymocytes and splenic T cells. Profoundly different two-dimensional thin layer chromatography (2D TLC) patterns were observed between these two cell types. Thymocytes contained 28-30 discrete gangliosides of which eight represented major gangliosides. Splenic T lymphocytes from both strains had much simpler patterns, with six to seven major gangliosides and 12-13 minor gangliosides. Computerized analysis of the thymocyte ganglioside patterns between LPS-responder C3H/HeN mice and lipopolysaccharide (LPS)-hyporesponsive C3H/HeJ mice revealed no significant difference in the major gangliosides. However, with splenic T cell gangliosides, there is a striking difference in the relative proportion of three homologous gangliosides between the two strains. Consistent with previous observations on macrophage gangliosides, the ratio of N-acetylneuraminic acid-containing ganglioside to N-glycolylneuraminic acid-containing ganglioside was higher in both thymocytes and T-cells from the LPS-responder strain. These results show that sialic acid-containing glycolipids from thymocytes and T lymphocytes between endotoxin responder and hyporesponder strains manifest small but significant changes. These differences are present in unstimulated cell populations and may represent a manifestation of the Lps gene. | lld:pubmed |
pubmed-article:3264007 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:3264007 | pubmed:language | eng | lld:pubmed |
pubmed-article:3264007 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:3264007 | pubmed:citationSubset | IM | lld:pubmed |
pubmed-article:3264007 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:3264007 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:3264007 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:3264007 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:3264007 | pubmed:status | MEDLINE | lld:pubmed |
pubmed-article:3264007 | pubmed:month | Dec | lld:pubmed |
pubmed-article:3264007 | pubmed:issn | 0741-5400 | lld:pubmed |
pubmed-article:3264007 | pubmed:author | pubmed-author:RyanJ LJL | lld:pubmed |
pubmed-article:3264007 | pubmed:author | pubmed-author:YoheH CHC | lld:pubmed |
pubmed-article:3264007 | pubmed:author | pubmed-author:BerensonC SCS | lld:pubmed |
pubmed-article:3264007 | pubmed:author | pubmed-author:CunyC LCL | lld:pubmed |
pubmed-article:3264007 | pubmed:issnType | Print | lld:pubmed |
pubmed-article:3264007 | pubmed:volume | 44 | lld:pubmed |
pubmed-article:3264007 | pubmed:owner | NLM | lld:pubmed |
pubmed-article:3264007 | pubmed:authorsComplete | Y | lld:pubmed |
pubmed-article:3264007 | pubmed:pagination | 521-8 | lld:pubmed |
pubmed-article:3264007 | pubmed:dateRevised | 2007-11-14 | lld:pubmed |
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pubmed-article:3264007 | pubmed:year | 1988 | lld:pubmed |
pubmed-article:3264007 | pubmed:articleTitle | Comparison of thymocyte and T lymphocyte gangliosides from C3H/HeN and C3H/HeJ mice. | lld:pubmed |
pubmed-article:3264007 | pubmed:affiliation | Department of Internal Medicine, Yale University School of Medicine, West Haven, CT 06516. | lld:pubmed |
pubmed-article:3264007 | pubmed:publicationType | Journal Article | lld:pubmed |
pubmed-article:3264007 | pubmed:publicationType | Comparative Study | lld:pubmed |
pubmed-article:3264007 | pubmed:publicationType | Research Support, U.S. Gov't, P.H.S. | lld:pubmed |
pubmed-article:3264007 | pubmed:publicationType | Research Support, U.S. Gov't, Non-P.H.S. | lld:pubmed |
http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:3264007 | lld:pubmed |