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pubmed-article:3262634pubmed:abstractTextTwo patients with solitary pulmonary nodules, 1.5-2.0 cm in diameter, were studied by positron emission tomography using [11C-Methyl]L-methionine (11C-Met). Case 1 showed high accumulation of 11C-Met in the tumor, and a tumor/muscle ratio of 6.0 suggesting malignancy. Tissue obtained by biopsy revealed a squamous cell carcinoma. Case 2 showed nonspecific isotope accumulation in the tumor, and a tumor/muscle ratio of 1.2 suggesting a benign lesion. Lung biopsy demonstrated granuloma. Positron emission tomography with 11C-Met seems to be useful for the differential diagnosis of solitary lung nodules.lld:pubmed
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pubmed-article:3262634pubmed:articleTitleDifferential diagnosis of solitary pulmonary nodules with positron emission tomography using [11C]L-methionine.lld:pubmed
pubmed-article:3262634pubmed:affiliationDepartment of Radiology and Nuclear Medicine, Tohoku University, Sendai, Japan.lld:pubmed
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