pubmed-article:3261260 | rdf:type | pubmed:Citation | lld:pubmed |
pubmed-article:3261260 | lifeskim:mentions | umls-concept:C1704336 | lld:lifeskim |
pubmed-article:3261260 | lifeskim:mentions | umls-concept:C0019134 | lld:lifeskim |
pubmed-article:3261260 | lifeskim:mentions | umls-concept:C1720154 | lld:lifeskim |
pubmed-article:3261260 | lifeskim:mentions | umls-concept:C1948027 | lld:lifeskim |
pubmed-article:3261260 | lifeskim:mentions | umls-concept:C0083009 | lld:lifeskim |
pubmed-article:3261260 | pubmed:issue | 1-2 | lld:pubmed |
pubmed-article:3261260 | pubmed:dateCreated | 1988-9-16 | lld:pubmed |
pubmed-article:3261260 | pubmed:abstractText | Heparin, an inhibitor of inositol trisphosphate (InsP3)-induced Ca2+ release in smooth muscle and non-muscle cells, was injected into intact frog skeletal muscle fibres. Ca2+ release from the sarcoplasmic reticulum was elicited by the normal action potential mechanism and monitored by both fura-2 fluorescence and an intrinsic birefringence signal. Both optical signals, and hence Ca2+ release, were unaffected by high concentrations of heparin. This result argues against a major physiological role of InsP3 as a chemical messenger of excitation-contraction coupling in skeletal muscle. | lld:pubmed |
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pubmed-article:3261260 | pubmed:language | eng | lld:pubmed |
pubmed-article:3261260 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:3261260 | pubmed:citationSubset | IM | lld:pubmed |
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pubmed-article:3261260 | pubmed:status | MEDLINE | lld:pubmed |
pubmed-article:3261260 | pubmed:month | Aug | lld:pubmed |
pubmed-article:3261260 | pubmed:issn | 0014-5793 | lld:pubmed |
pubmed-article:3261260 | pubmed:author | pubmed-author:SomlyoA PAP | lld:pubmed |
pubmed-article:3261260 | pubmed:author | pubmed-author:BaylorS MSM | lld:pubmed |
pubmed-article:3261260 | pubmed:author | pubmed-author:KonishiMM | lld:pubmed |
pubmed-article:3261260 | pubmed:author | pubmed-author:PapeP CPC | lld:pubmed |
pubmed-article:3261260 | pubmed:issnType | Print | lld:pubmed |
pubmed-article:3261260 | pubmed:day | 1 | lld:pubmed |
pubmed-article:3261260 | pubmed:volume | 235 | lld:pubmed |
pubmed-article:3261260 | pubmed:owner | NLM | lld:pubmed |
pubmed-article:3261260 | pubmed:authorsComplete | Y | lld:pubmed |
pubmed-article:3261260 | pubmed:pagination | 57-62 | lld:pubmed |
pubmed-article:3261260 | pubmed:dateRevised | 2007-11-14 | lld:pubmed |
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pubmed-article:3261260 | pubmed:meshHeading | pubmed-meshheading:3261260-... | lld:pubmed |
pubmed-article:3261260 | pubmed:year | 1988 | lld:pubmed |
pubmed-article:3261260 | pubmed:articleTitle | Excitation-contraction coupling in skeletal muscle fibers injected with the InsP3 blocker, heparin. | lld:pubmed |
pubmed-article:3261260 | pubmed:affiliation | Department of Physiology, University of Pennsylvania School of Medicine, Philadelphia 19104-6085. | lld:pubmed |
pubmed-article:3261260 | pubmed:publicationType | Journal Article | lld:pubmed |
pubmed-article:3261260 | pubmed:publicationType | Research Support, U.S. Gov't, P.H.S. | lld:pubmed |
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