pubmed-article:3257748 | rdf:type | pubmed:Citation | lld:pubmed |
pubmed-article:3257748 | lifeskim:mentions | umls-concept:C0085488 | lld:lifeskim |
pubmed-article:3257748 | lifeskim:mentions | umls-concept:C0024432 | lld:lifeskim |
pubmed-article:3257748 | lifeskim:mentions | umls-concept:C0021755 | lld:lifeskim |
pubmed-article:3257748 | lifeskim:mentions | umls-concept:C0032594 | lld:lifeskim |
pubmed-article:3257748 | lifeskim:mentions | umls-concept:C0023810 | lld:lifeskim |
pubmed-article:3257748 | lifeskim:mentions | umls-concept:C0030685 | lld:lifeskim |
pubmed-article:3257748 | lifeskim:mentions | umls-concept:C0680255 | lld:lifeskim |
pubmed-article:3257748 | lifeskim:mentions | umls-concept:C0391871 | lld:lifeskim |
pubmed-article:3257748 | lifeskim:mentions | umls-concept:C1283071 | lld:lifeskim |
pubmed-article:3257748 | lifeskim:mentions | umls-concept:C1963578 | lld:lifeskim |
pubmed-article:3257748 | lifeskim:mentions | umls-concept:C0449719 | lld:lifeskim |
pubmed-article:3257748 | lifeskim:mentions | umls-concept:C0591833 | lld:lifeskim |
pubmed-article:3257748 | lifeskim:mentions | umls-concept:C0301625 | lld:lifeskim |
pubmed-article:3257748 | pubmed:issue | 3 | lld:pubmed |
pubmed-article:3257748 | pubmed:dateCreated | 1988-3-30 | lld:pubmed |
pubmed-article:3257748 | pubmed:abstractText | Lipopolysaccharide (LPS) was extracted from whole cells of Haemophilus actinomycetemcomitans Y4 by the hot phenol-water procedure. LPS was cleaved into its lipid A and polysaccharide moieties by hydrolysis in 1% acetic acid. The major component sugars of the polysaccharide were glucose, heptose, rhamnose, galactose, and fucose. LPS and lipid A from H. actinomycetemcomitans induced the release of interleukin-1 (IL-1) by LPS-responsive C3H/HeN murine peritoneal macrophages and cell line macrophages (P388D1 and J744.1), but not by LPS-nonresponsive C3H/HeJ peritoneal macrophages. The polysaccharide was unable to induce the release of IL-1. It suppressed the IL-1 release from LPS- and lipid A-stimulated macrophages, but not the production of cell-associated and intracellular IL-1. The addition of rhamnose, a sugar component of the polysaccharide, abrogated the inhibitory effect of the polysaccharide on IL-1 release. These results suggest the participation of a lectinlike molecule in IL-1 release. | lld:pubmed |
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pubmed-article:3257748 | pubmed:language | eng | lld:pubmed |
pubmed-article:3257748 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:3257748 | pubmed:citationSubset | IM | lld:pubmed |
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pubmed-article:3257748 | pubmed:status | MEDLINE | lld:pubmed |
pubmed-article:3257748 | pubmed:month | Mar | lld:pubmed |
pubmed-article:3257748 | pubmed:issn | 0019-9567 | lld:pubmed |
pubmed-article:3257748 | pubmed:author | pubmed-author:HamadaSS | lld:pubmed |
pubmed-article:3257748 | pubmed:author | pubmed-author:NishiharaTT | lld:pubmed |
pubmed-article:3257748 | pubmed:author | pubmed-author:KogaTT | lld:pubmed |
pubmed-article:3257748 | pubmed:issnType | Print | lld:pubmed |
pubmed-article:3257748 | pubmed:volume | 56 | lld:pubmed |
pubmed-article:3257748 | pubmed:owner | NLM | lld:pubmed |
pubmed-article:3257748 | pubmed:authorsComplete | Y | lld:pubmed |
pubmed-article:3257748 | pubmed:pagination | 619-25 | lld:pubmed |
pubmed-article:3257748 | pubmed:dateRevised | 2009-11-18 | lld:pubmed |
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pubmed-article:3257748 | pubmed:year | 1988 | lld:pubmed |
pubmed-article:3257748 | pubmed:articleTitle | Suppression of murine macrophage interleukin-1 release by the polysaccharide portion of Haemophilus actinomycetemcomitans lipopolysaccharide. | lld:pubmed |
pubmed-article:3257748 | pubmed:affiliation | Department of Dental Research, National Institute of Health, Tokyo, Japan. | lld:pubmed |
pubmed-article:3257748 | pubmed:publicationType | Journal Article | lld:pubmed |
pubmed-article:3257748 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
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