| pubmed-article:3226923 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:3226923 | lifeskim:mentions | umls-concept:C0023493 | lld:lifeskim |
| pubmed-article:3226923 | lifeskim:mentions | umls-concept:C0007634 | lld:lifeskim |
| pubmed-article:3226923 | lifeskim:mentions | umls-concept:C0012893 | lld:lifeskim |
| pubmed-article:3226923 | lifeskim:mentions | umls-concept:C1524063 | lld:lifeskim |
| pubmed-article:3226923 | lifeskim:mentions | umls-concept:C1880022 | lld:lifeskim |
| pubmed-article:3226923 | pubmed:issue | 19 | lld:pubmed |
| pubmed-article:3226923 | pubmed:dateCreated | 1989-3-29 | lld:pubmed |
| pubmed-article:3226923 | pubmed:abstractText | DNA fragments were labeled with dinitrophenyl (DNP) residues by the reaction with 2,4-dinitrobenzaldehyde in alkaline condition and the labeled DNA was used as a probe for non-radioactive in situ hybridization. DNP-labeled DNA probes for T cell receptor beta chain, c-myc and HTLV-1 were hybridized in situ to mRNA on cell specimens fixed with Carnoy's fixative. DNA-mRNA hybrids were detected immunohistochemically using anti-DNP antibodies. Cytoplasms of adult T cell leukemia cells were stained with varied intensity when these probes were used. More than 70% of cells were positively stained with T cell receptor probe. However, less than 30% of cells were stained with c-myc and HTLV-1 probes. The present study indicates that non-radioactive in situ hybridization can be used for the characterization and classification of leukemia. | lld:pubmed |
| pubmed-article:3226923 | pubmed:language | eng | lld:pubmed |
| pubmed-article:3226923 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:3226923 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:3226923 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:3226923 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:3226923 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:3226923 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:3226923 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:3226923 | pubmed:issn | 0261-3166 | lld:pubmed |
| pubmed-article:3226923 | pubmed:author | pubmed-author:YoshidaMM | lld:pubmed |
| pubmed-article:3226923 | pubmed:author | pubmed-author:NakaneP KPK | lld:pubmed |
| pubmed-article:3226923 | pubmed:author | pubmed-author:KojiTT | lld:pubmed |
| pubmed-article:3226923 | pubmed:author | pubmed-author:MoriuchiJJ | lld:pubmed |
| pubmed-article:3226923 | pubmed:author | pubmed-author:MoriuchiTT | lld:pubmed |
| pubmed-article:3226923 | pubmed:author | pubmed-author:ArimoriSS | lld:pubmed |
| pubmed-article:3226923 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:3226923 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:3226923 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:3226923 | pubmed:pagination | 77-80 | lld:pubmed |
| pubmed-article:3226923 | pubmed:dateRevised | 2006-11-15 | lld:pubmed |
| pubmed-article:3226923 | pubmed:meshHeading | pubmed-meshheading:3226923-... | lld:pubmed |
| pubmed-article:3226923 | pubmed:meshHeading | pubmed-meshheading:3226923-... | lld:pubmed |
| pubmed-article:3226923 | pubmed:meshHeading | pubmed-meshheading:3226923-... | lld:pubmed |
| pubmed-article:3226923 | pubmed:meshHeading | pubmed-meshheading:3226923-... | lld:pubmed |
| pubmed-article:3226923 | pubmed:meshHeading | pubmed-meshheading:3226923-... | lld:pubmed |
| pubmed-article:3226923 | pubmed:meshHeading | pubmed-meshheading:3226923-... | lld:pubmed |
| pubmed-article:3226923 | pubmed:meshHeading | pubmed-meshheading:3226923-... | lld:pubmed |
| pubmed-article:3226923 | pubmed:meshHeading | pubmed-meshheading:3226923-... | lld:pubmed |
| pubmed-article:3226923 | pubmed:meshHeading | pubmed-meshheading:3226923-... | lld:pubmed |
| pubmed-article:3226923 | pubmed:meshHeading | pubmed-meshheading:3226923-... | lld:pubmed |
| pubmed-article:3226923 | pubmed:meshHeading | pubmed-meshheading:3226923-... | lld:pubmed |
| pubmed-article:3226923 | pubmed:meshHeading | pubmed-meshheading:3226923-... | lld:pubmed |
| pubmed-article:3226923 | pubmed:meshHeading | pubmed-meshheading:3226923-... | lld:pubmed |
| pubmed-article:3226923 | pubmed:year | 1988 | lld:pubmed |
| pubmed-article:3226923 | pubmed:articleTitle | Use of non-radioactive DNA probes for the characterization of adult T-cell leukemia cells. | lld:pubmed |
| pubmed-article:3226923 | pubmed:affiliation | Department of Cell Biology, Tokai University School of Medicine, Isehara, Japan. | lld:pubmed |
| pubmed-article:3226923 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:3226923 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:3226923 | lld:pubmed |
