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pubmed-article:3210017pubmed:abstractTextTwo new cytotoxic chromene derivatives, butyrylmallotochromene [10] and isobutyrylmallotochromene [11], were isolated from the pericarps of Mallotus japonicus. The new derivatives were identified as 5,7-dihydroxy-6-(2',4'-dihydroxy-3'-acetyl-5'-methyl-6'-methoxybenzyl)-8 - butyryl-2,2-dimethylchromene [10] and 5,7-dihydroxy-6-(2',4'-dihydroxy-3'-acetyl-5'-methyl-6'-methoxybenzyl)-8 - isobutyryl-2,2-dimethylchromene [11] by means of spectral data. These compounds and their respective acetylation and methylation products were found to be cytotoxic against KB cell lines.lld:pubmed
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pubmed-article:3210017pubmed:authorpubmed-author:ShimizuMMlld:pubmed
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pubmed-article:3210017pubmed:dateRevised2008-11-21lld:pubmed
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pubmed-article:3210017pubmed:articleTitleStudies on cytotoxic constituents in pericarps of Mallotus japonicus, Part III.lld:pubmed
pubmed-article:3210017pubmed:affiliationDepartment of Medicinal Resources, Faculty of Pharmaceutical Sciences, Toyama Medical and Pharmaceutical University, Japan.lld:pubmed
pubmed-article:3210017pubmed:publicationTypeJournal Articlelld:pubmed
pubmed-article:3210017pubmed:publicationTypeResearch Support, Non-U.S. Gov'tlld:pubmed