pubmed-article:3198243 | rdf:type | pubmed:Citation | lld:pubmed |
pubmed-article:3198243 | lifeskim:mentions | umls-concept:C0085979 | lld:lifeskim |
pubmed-article:3198243 | lifeskim:mentions | umls-concept:C0020885 | lld:lifeskim |
pubmed-article:3198243 | lifeskim:mentions | umls-concept:C0178702 | lld:lifeskim |
pubmed-article:3198243 | lifeskim:mentions | umls-concept:C1704632 | lld:lifeskim |
pubmed-article:3198243 | lifeskim:mentions | umls-concept:C0871261 | lld:lifeskim |
pubmed-article:3198243 | lifeskim:mentions | umls-concept:C2911692 | lld:lifeskim |
pubmed-article:3198243 | lifeskim:mentions | umls-concept:C1706817 | lld:lifeskim |
pubmed-article:3198243 | pubmed:issue | 3 | lld:pubmed |
pubmed-article:3198243 | pubmed:dateCreated | 1989-1-17 | lld:pubmed |
pubmed-article:3198243 | pubmed:abstractText | The present study was undertaken to investigate the autoinhibition and desensitization of 5-hydroxytryptamine (5-HT) using another agonist MK-212 on guinea pig ileum. 5-HT and MK-212 produced dose dependent contractions of guinea pig ileum. The responses to MK-212 were reduced in the presence of 5-HT and vice versa. Neither 5-HT nor MK-212 produced any change in the responses to histamine, acetylcholine or KCl. Increase in Ca++ in bathing fluid reversed the desensitization produced by MK-212 or 5-HT. Our data suggest that 5-HT and MK-212 produce desensitization which is specific for serotonergic receptors and possibly involves Ca++ ions. | lld:pubmed |
pubmed-article:3198243 | pubmed:language | eng | lld:pubmed |
pubmed-article:3198243 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:3198243 | pubmed:citationSubset | IM | lld:pubmed |
pubmed-article:3198243 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:3198243 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:3198243 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:3198243 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:3198243 | pubmed:status | MEDLINE | lld:pubmed |
pubmed-article:3198243 | pubmed:issn | 0019-5499 | lld:pubmed |
pubmed-article:3198243 | pubmed:author | pubmed-author:GoyalR KRK | lld:pubmed |
pubmed-article:3198243 | pubmed:author | pubmed-author:JoshiD PDP | lld:pubmed |
pubmed-article:3198243 | pubmed:author | pubmed-author:MehtaA AAA | lld:pubmed |
pubmed-article:3198243 | pubmed:author | pubmed-author:ChinmayeeNN | lld:pubmed |
pubmed-article:3198243 | pubmed:issnType | Print | lld:pubmed |
pubmed-article:3198243 | pubmed:volume | 32 | lld:pubmed |
pubmed-article:3198243 | pubmed:owner | NLM | lld:pubmed |
pubmed-article:3198243 | pubmed:authorsComplete | Y | lld:pubmed |
pubmed-article:3198243 | pubmed:pagination | 215-20 | lld:pubmed |
pubmed-article:3198243 | pubmed:dateRevised | 2006-11-15 | lld:pubmed |
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pubmed-article:3198243 | pubmed:articleTitle | Autoinhibition and desensitization of serotonergic responses in guinea pig ileum. | lld:pubmed |
pubmed-article:3198243 | pubmed:affiliation | Department of Pharmacology, L. M. College of Pharmacy, Navrangpura, Ahmedabad. | lld:pubmed |
pubmed-article:3198243 | pubmed:publicationType | Journal Article | lld:pubmed |
pubmed-article:3198243 | pubmed:publicationType | In Vitro | lld:pubmed |