| pubmed-article:3182782 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:3182782 | lifeskim:mentions | umls-concept:C0030705 | lld:lifeskim |
| pubmed-article:3182782 | lifeskim:mentions | umls-concept:C0020792 | lld:lifeskim |
| pubmed-article:3182782 | lifeskim:mentions | umls-concept:C0003964 | lld:lifeskim |
| pubmed-article:3182782 | lifeskim:mentions | umls-concept:C0024623 | lld:lifeskim |
| pubmed-article:3182782 | lifeskim:mentions | umls-concept:C0006100 | lld:lifeskim |
| pubmed-article:3182782 | lifeskim:mentions | umls-concept:C1998793 | lld:lifeskim |
| pubmed-article:3182782 | pubmed:issue | 31 | lld:pubmed |
| pubmed-article:3182782 | pubmed:dateCreated | 1988-12-2 | lld:pubmed |
| pubmed-article:3182782 | pubmed:abstractText | Kinins in the ascitic fluid from a patient with gastric cancer were purified by gel filtration and reversed-phase high-performance liquid chromatography (HPLC). Two fractions (fractions I and II) showed kinin activity. Fraction I did not correspond to either bradykinin or other known kinins, whereas fraction II corresponded to bradykinin. Fraction I contained 8 amino acid residues from bradykinin minus 1 proline plus 1 additional hydroxyproline. Sequence analysis of fraction I showed that the proline at the third amino acid residue of bradykinin was replaced by hydroxyproline. The retention time of fraction I on reversed-phase HPLC was exactly the same as that of synthetic [hydroxyprolyl3]bradykinin (Arg-Pro-Hyp-Gly-Phe-Ser-Pro-Phe-Arg) and was distinguishable from des-Pro3-bradykinin. Thus, these results demonstrate for the first time the presence of [hydroxyprolyl3]bradykinin in vivo. This is also the first report of the presence of bradykinin in human tumor ascites. | lld:pubmed |
| pubmed-article:3182782 | pubmed:language | eng | lld:pubmed |
| pubmed-article:3182782 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:3182782 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:3182782 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:3182782 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:3182782 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:3182782 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:3182782 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:3182782 | pubmed:month | Nov | lld:pubmed |
| pubmed-article:3182782 | pubmed:issn | 0021-9258 | lld:pubmed |
| pubmed-article:3182782 | pubmed:author | pubmed-author:MaedaHH | lld:pubmed |
| pubmed-article:3182782 | pubmed:author | pubmed-author:MatsumuraYY | lld:pubmed |
| pubmed-article:3182782 | pubmed:author | pubmed-author:KatzEE | lld:pubmed |
| pubmed-article:3182782 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:3182782 | pubmed:day | 5 | lld:pubmed |
| pubmed-article:3182782 | pubmed:volume | 263 | lld:pubmed |
| pubmed-article:3182782 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:3182782 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:3182782 | pubmed:pagination | 16051-4 | lld:pubmed |
| pubmed-article:3182782 | pubmed:dateRevised | 2006-11-15 | lld:pubmed |
| pubmed-article:3182782 | pubmed:meshHeading | pubmed-meshheading:3182782-... | lld:pubmed |
| pubmed-article:3182782 | pubmed:meshHeading | pubmed-meshheading:3182782-... | lld:pubmed |
| pubmed-article:3182782 | pubmed:meshHeading | pubmed-meshheading:3182782-... | lld:pubmed |
| pubmed-article:3182782 | pubmed:meshHeading | pubmed-meshheading:3182782-... | lld:pubmed |
| pubmed-article:3182782 | pubmed:meshHeading | pubmed-meshheading:3182782-... | lld:pubmed |
| pubmed-article:3182782 | pubmed:meshHeading | pubmed-meshheading:3182782-... | lld:pubmed |
| pubmed-article:3182782 | pubmed:meshHeading | pubmed-meshheading:3182782-... | lld:pubmed |
| pubmed-article:3182782 | pubmed:meshHeading | pubmed-meshheading:3182782-... | lld:pubmed |
| pubmed-article:3182782 | pubmed:meshHeading | pubmed-meshheading:3182782-... | lld:pubmed |
| pubmed-article:3182782 | pubmed:meshHeading | pubmed-meshheading:3182782-... | lld:pubmed |
| pubmed-article:3182782 | pubmed:year | 1988 | lld:pubmed |
| pubmed-article:3182782 | pubmed:articleTitle | Purification and identification of [hydroxyprolyl3]bradykinin in ascitic fluid from a patient with gastric cancer. | lld:pubmed |
| pubmed-article:3182782 | pubmed:affiliation | Department of Microbiology, Kumamoto University Medical School, Japan. | lld:pubmed |
| pubmed-article:3182782 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:3182782 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
| entrez-gene:3827 | entrezgene:pubmed | pubmed-article:3182782 | lld:entrezgene |
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