pubmed-article:3182490 | rdf:type | pubmed:Citation | lld:pubmed |
pubmed-article:3182490 | lifeskim:mentions | umls-concept:C0026727 | lld:lifeskim |
pubmed-article:3182490 | lifeskim:mentions | umls-concept:C0005528 | lld:lifeskim |
pubmed-article:3182490 | pubmed:issue | 3 | lld:pubmed |
pubmed-article:3182490 | pubmed:dateCreated | 1988-12-7 | lld:pubmed |
pubmed-article:3182490 | pubmed:abstractText | To study air-mucus interaction as a possible mechanism of tracheal mucus transport and to test the validity of using surface tracer displacement to indicate bulk mucus transport, we performed a combined experimental-theoretical study. We hypothesized that the mucus mass is moved by the difference between expiratory and inspiratory velocities. The rate of transport of a layer of simulated mucus lining the bottom of a rectangular trough was measured in two ways during oscillatory air flow. Peak velocity ratios (R) from 1.0 to 2.0, frequencies (f) between 7 and 13 Hz, and tidal volumes (VT) between 50 and 100 ml were generated by a custom-made pump. The experimental results demonstrate that measuring the displacement of a tracer deposited on the surface of the mucus layer is equivalent to measuring bulk mucus movement by weight. Moreover the measured mucus velocities (micron) correlate well with a theoretical model which predicts that micron is proportional to delta VT f1.5 (R-1). These results suggest that shearing at the air-mucus interface could be a significant factor in the enhanced tracheal mucus clearance during high-frequency chest wall oscillation. | lld:pubmed |
pubmed-article:3182490 | pubmed:language | eng | lld:pubmed |
pubmed-article:3182490 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:3182490 | pubmed:citationSubset | IM | lld:pubmed |
pubmed-article:3182490 | pubmed:status | MEDLINE | lld:pubmed |
pubmed-article:3182490 | pubmed:month | Sep | lld:pubmed |
pubmed-article:3182490 | pubmed:issn | 8750-7587 | lld:pubmed |
pubmed-article:3182490 | pubmed:author | pubmed-author:KingMM | lld:pubmed |
pubmed-article:3182490 | pubmed:author | pubmed-author:WeberM EME | lld:pubmed |
pubmed-article:3182490 | pubmed:author | pubmed-author:ChangH KHK | lld:pubmed |
pubmed-article:3182490 | pubmed:issnType | Print | lld:pubmed |
pubmed-article:3182490 | pubmed:volume | 65 | lld:pubmed |
pubmed-article:3182490 | pubmed:owner | NLM | lld:pubmed |
pubmed-article:3182490 | pubmed:authorsComplete | Y | lld:pubmed |
pubmed-article:3182490 | pubmed:pagination | 1203-9 | lld:pubmed |
pubmed-article:3182490 | pubmed:dateRevised | 2006-11-15 | lld:pubmed |
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pubmed-article:3182490 | pubmed:year | 1988 | lld:pubmed |
pubmed-article:3182490 | pubmed:articleTitle | Mucus transport by high-frequency nonsymmetrical oscillatory airflow. | lld:pubmed |
pubmed-article:3182490 | pubmed:affiliation | Department of Biomedical Engineering, University of Southern California, Los Angeles 90089-1451. | lld:pubmed |
pubmed-article:3182490 | pubmed:publicationType | Journal Article | lld:pubmed |
pubmed-article:3182490 | pubmed:publicationType | In Vitro | lld:pubmed |