| pubmed-article:3181397 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:3181397 | lifeskim:mentions | umls-concept:C0008059 | lld:lifeskim |
| pubmed-article:3181397 | lifeskim:mentions | umls-concept:C0023449 | lld:lifeskim |
| pubmed-article:3181397 | lifeskim:mentions | umls-concept:C0200896 | lld:lifeskim |
| pubmed-article:3181397 | pubmed:issue | 3 | lld:pubmed |
| pubmed-article:3181397 | pubmed:dateCreated | 1988-11-29 | lld:pubmed |
| pubmed-article:3181397 | pubmed:abstractText | Cytogenetic analysis was performed on 105 children with acute lymphoblastic leukemia (ALL). Adequate mitoses for study were obtained in 79 of the cases (71%). A normal karyotype was found in 18 patients (23%), while clonal chromosomal abnormalities were detected in 61 patients (77%). The karyotypes fell into five categories according to modal number: normal (18 patients), pseudodiploid (27 patients), hypodiploid (3 patients), hyperdiploid with 47-50 chromosomes (11 patients), and hyperdiploid with greater than or equal to 51 chromosomes (20 patients). Structural chromosome changes were found in 50 patients (63%); translocations were encountered in 15 of these patients (19%). The chromosome most often participating in translocations was number 19. Modal number was found to be an independent prognostic factor. Modal numbers 47-50 were associated with the poorest prognosis. The hyperdiploid clone with more than 50 chromosomes and the normal karyotype had the best prognosis. | lld:pubmed |
| pubmed-article:3181397 | pubmed:language | eng | lld:pubmed |
| pubmed-article:3181397 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:3181397 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:3181397 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:3181397 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:3181397 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:3181397 | pubmed:month | Sep | lld:pubmed |
| pubmed-article:3181397 | pubmed:issn | 0902-4441 | lld:pubmed |
| pubmed-article:3181397 | pubmed:author | pubmed-author:HeinonenKK | lld:pubmed |
| pubmed-article:3181397 | pubmed:author | pubmed-author:SiimesM AMA | lld:pubmed |
| pubmed-article:3181397 | pubmed:author | pubmed-author:KnuutilaSS | lld:pubmed |
| pubmed-article:3181397 | pubmed:author | pubmed-author:RautonenJJ | lld:pubmed |
| pubmed-article:3181397 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:3181397 | pubmed:volume | 41 | lld:pubmed |
| pubmed-article:3181397 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:3181397 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:3181397 | pubmed:pagination | 237-42 | lld:pubmed |
| pubmed-article:3181397 | pubmed:dateRevised | 2007-11-15 | lld:pubmed |
| pubmed-article:3181397 | pubmed:meshHeading | pubmed-meshheading:3181397-... | lld:pubmed |
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| pubmed-article:3181397 | pubmed:meshHeading | pubmed-meshheading:3181397-... | lld:pubmed |
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| pubmed-article:3181397 | pubmed:meshHeading | pubmed-meshheading:3181397-... | lld:pubmed |
| pubmed-article:3181397 | pubmed:meshHeading | pubmed-meshheading:3181397-... | lld:pubmed |
| pubmed-article:3181397 | pubmed:meshHeading | pubmed-meshheading:3181397-... | lld:pubmed |
| pubmed-article:3181397 | pubmed:meshHeading | pubmed-meshheading:3181397-... | lld:pubmed |
| pubmed-article:3181397 | pubmed:meshHeading | pubmed-meshheading:3181397-... | lld:pubmed |
| pubmed-article:3181397 | pubmed:meshHeading | pubmed-meshheading:3181397-... | lld:pubmed |
| pubmed-article:3181397 | pubmed:meshHeading | pubmed-meshheading:3181397-... | lld:pubmed |
| pubmed-article:3181397 | pubmed:year | 1988 | lld:pubmed |
| pubmed-article:3181397 | pubmed:articleTitle | Cytogenetic study of 105 children with acute lymphoblastic leukemia. | lld:pubmed |
| pubmed-article:3181397 | pubmed:affiliation | Department of Medical Genetics, University of Helsinki, Finland. | lld:pubmed |
| pubmed-article:3181397 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:3181397 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:3181397 | lld:pubmed |
